Baricitinib Impurity 11 CAS CATO-C4X-226011
| CAS No. | CATO-C4X-226011 |
| Molecular Formula | C14H17N5O2 |
| Molecular Weight | 287.32 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Baricitinib Impurity 11 (CAS CATO-C4X-226011, C14H17N5O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Baricitinib Impurity 11 (C14H17N5O2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
CATO manufactures Baricitinib Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C14H17N5O2 |
| Molecular Weight | 287.32 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Baricitinib Standards
- Baricitinib Impurity 125 (CAS 1416785-38-0)
- Baricitinib Impurity 15 (CAS 941685-26-3)
- Baricitinib Impurity 124 (CAS CATO-C4X-2260124)
- Baricitinib Impurity 74 (CAS CATO-C4X-226074)
- Baricitinib Impurity N7 (CAS 1187594-16-6)
- Baricitinib Impurity 93 (CAS CATO-C4X-226093)
- Baricitinib Impurity 129 (CAS 3043892-25-4)
- Baricitinib Impurity 48 (CAS CATO-C4X-226048)
Recommended Standards
- Palbociclib Impurity 49 (CAS 2172256-78-7)
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- 2-{[(3,4-dimethylphenyl)sulfonyl]amino}-3-hydroxybutanoic acid (CAS 1008068-91-4)
- Nintedanib Impurity N4 (CAS 1987887-92-2)
- Indobufen Impurity 82 (CAS CATO-C4X-179282)
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- [(1R,3R)-3-aminocyclohexyl]methanol;hydrochloride (CAS 2416138-46-8)
- 5-Bromo-2-cyano-3-iodobenzoic acid (CAS 1805595-09-8)
- N-{4-[4-(4-chlorobenzenesulfonyl)piperazin-1-yl]-3-fluorophenyl}-3-methylbenzamide (CAS 478260-29-6)
- Methyl 3,5-diiodo-4-methoxybenzoate (CAS 4253-10-5)
- Insulin Degludec Impurity 27 (CAS CATO-C4X-215727)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com