Baricitinib Impurity 137 CAS CATO-C4X-2260137
| CAS No. | CATO-C4X-2260137 |
| Molecular Formula | C15H19N7O4S |
| Molecular Weight | 393.42 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Baricitinib Impurity 137 (C15H19N7O4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Baricitinib Impurity 137 (CAS CATO-C4X-2260137, C15H19N7O4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Baricitinib Impurity 137 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H19N7O4S |
| Molecular Weight | 393.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Baricitinib Standards
- Baricitinib Impurity 130 (CAS CATO-C4X-2260130)
- Baricitinib Impurity 88 (CAS CATO-C4X-226088)
- Baricitinib Impurity 1 (CAS 2964606-42-4)
- Baricitinib Impurity 114 (CAS CATO-C4X-2260114)
- Baricitinib Impurity 49 (CAS CATO-C4X-226049)
- Baricitinib Impurity 5 (CAS 2271228-52-3)
- Baricitinib Impurity 52 (CAS 2910813-43-1)
- Baricitinib Impurity 103 (CAS CATO-C4X-2260103)
Recommended Standards
- N-{3-[(2-fluorophenyl)thio]propyl}-3-(trifluoromethyl)benzenesulphonamide (CAS 648408-66-6)
- Tegoprazan D6 (CAS CATO-C4X-229761)
- N-(6-Acetyl-3-cyano-4,5,6,7-tetrahydrothieno[2,3-c]pyridin-2-yl)-2-oxo-2H-chromene-3-carboxamide (CAS 864858-73-1)
- Methyl 3-cyclopropyl-1-(4-fluorophenyl)-6-(thiophen-2-yl)-1H-pyrazolo[3,4-b]pyridine-4-carboxylate (CAS 1011398-16-5)
- Eltrombopag Impurity 84 (CAS CATO-C4X-119884)
- Opicapone impurity 29 (CAS CATO-C4X-240429)
- Apixaban Impurity 180 (CAS CATO-C4X-1088180)
- N-Methyl-1-(3-methylpyrazin-2-yl)piperidin-4-amine hydrochloride (CAS 1289386-19-1)
- 1-(3-Chlorophenyl)-3-(4-chlorophenyl)-1H-pyrazole-5-carboxylic acid (CAS 618102-47-9)
- 2-Chloro-1-iodo-4-isocyanatobenzene (CAS 1261790-72-0)
- Cinoxacin (CAS 28657-80-9)
- 5-(2-Chloropropanoyl)-1,3-dihydro-2H-benzo[d]imidazol-2-one (CAS 127806-48-8)
- 1-Ethoxycyclohex-1-ene (CAS 1122-84-5)
- D-[Val]10-Semaglutide (CAS CATO-CPTD788630)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com