Ponatinib Impurity 47 CAS CATO-C4X-226947
| CAS No. | CATO-C4X-226947 |
| Molecular Formula | C13H16F3N3O2 |
| Molecular Weight | 303.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Ponatinib Impurity 47 (CAS CATO-C4X-226947, C13H16F3N3O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H16F3N3O2, Ponatinib Impurity 47 contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 303.28 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO manufactures Ponatinib Impurity 47 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H16F3N3O2 |
| Molecular Weight | 303.28 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Ponatinib Standards
- Ponatinib Impurity 48 (CAS CATO-C4X-226948)
- Ponatinib Impurity 49 (CAS 1952344-01-2)
- Ponatinib Impurity 38 (CAS 2755819-36-2)
- Ponatinib Impurity 57 (CAS CATO-C4X-226957)
- Ponatinib Impurity 56 (CAS CATO-C4X-226956)
- Ponatinib impurity 7 (CAS 1300690-48-5)
- Ponatinib Impurity 50 (CAS 1781021-72-4)
- Ponatinib Impurity 51 (CAS 94224-92-7)
Recommended Standards
- tert-Butyl 2-(trifluoromethyl)-5,6-dihydropyrido[3,4-d]pyrimidine-7(8H)-carboxylate (CAS 877402-39-6)
- N'-(6-amino-1-(2-hydroxyethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-yl)furan-2-carbohydrazide (CAS 377729-86-7)
- N-(3-Ethynylphenyl)-4-methyl-3-(trifluoromethyl)benzamide (CAS 2499499-11-3)
- Diosmetin-d3 (CAS 1189728-54-8)
- Glycopyrronium Bromide Impurity8 (CAS CATO-C4X-18178)
- Posaconazole Impurity 25 (CAS 1042398-26-4)
- Atrasentan Impurity 174 (CAS 1059051-97-6)
- N-(3,4-Dichlorophenyl)tetrahydrofuran-2-carboxamide (CAS 545340-98-5)
- 6-Chloro-2-(4-propylphenyl)quinoline-4-carboxylic acid (CAS 932886-69-6)
- Tetrabenazine Impurity 65 HCl (CAS 1162658-07-2 (free base))
- 4-Acetyl-2,5-dimethyl-1H-pyrrole-3-carbonitrile (CAS 67271-65-2)
- Bis((dibutoxyphosphorothioyl)thio)zinc (CAS 6990-43-8)
- 2-Aminopropanenitrile Hydrochloride (CAS 72187-91-8)
- Glucagon-like peptide 2 (CAS 89750-15-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com