Upadacitinib Impurity 131 CAS CATO-C4X-2405131
| CAS No. | CATO-C4X-2405131 |
| Molecular Formula | C27H33N5O5 |
| Molecular Weight | 507.58 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Upadacitinib Impurity 131.
Upadacitinib Impurity 131 (CAS CATO-C4X-2405131) is a certified pharmaceutical impurity reference standard with the molecular formula C27H33N5O5 and a molecular weight of 507.58 g/mol.
Upadacitinib Impurity 131 (C27H33N5O5) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Upadacitinib Impurity 131 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H33N5O5 |
| Molecular Weight | 507.58 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Upadacitinib Standards
- Upadacitinib Impurity 135 (CAS CATO-C4X-2405135)
- Upadacitinib Impurity 5 (CAS CATO-C4X-24055)
- Upadacitinib Impurity 168 (CAS CATO-C4X-2405168)
- Upadacitinib Impurity 213 (CAS 2768445-19-6)
- Upadacitinib Impurity 193 (CAS CATO-C4X-2405193)
- Upadacitinib Impurity 21 (CAS 2715120-86-6)
- Upadacitinib Impurity 130 (CAS CATO-C4X-2405130)
- Upadacitinib Impurity 210 (CAS CATO-C4X-2405210)
Recommended Standards
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- Labetalol Impurity 46 (CAS CATO-C4X-246646)
- Vinorelbine EP Impurity I (CAS CATO-C4X-264210)
- Sertraline Impurity 68 (CAS CATO-C4X-134468)
- Neomycin EP Impurity B (CAS 54617-39-9)
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- Methyl 2-(6-hydroxy-4-methylbenzofuran-3-yl)acetate (CAS 1380390-22-6)
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- 4,4,5,5-tetramethyl-2-[cis-2-methylcyclopropyl]-1,3,2-dioxaborolane (CAS 1309366-00-4)
- Tau Peptide (301-315) trifluoroacetate salt (CAS 330456-48-9)
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