Upadacitinib Impurity 140 CAS CATO-C4X-2405140
| CAS No. | CATO-C4X-2405140 |
| Molecular Formula | C17H23NO4S |
| Molecular Weight | 337.43 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), Upadacitinib Impurity 140 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
As a process- or degradation-related impurity, Upadacitinib Impurity 140 (CAS CATO-C4X-2405140, C17H23NO4S) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Upadacitinib Impurity 140 (C17H23NO4S) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Physical & Chemical Properties
| Molecular Formula | C17H23NO4S |
| Molecular Weight | 337.43 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 141 (CAS CATO-C4X-2405141)
- Upadacitinib Impurity 57 (CAS CATO-C4X-240557)
- Upadacitinib Impurity 182 (CAS 1428243-39-3)
- Upadacitinib Impurity 1 (CAS CATO-C4X-24051)
- Upadacitinib Impurity 169 (CAS CATO-C4X-2405169)
- Upadacitinib Impurity 101 (CAS CATO-C4X-2405101)
- Upadacitinib Impurity 143 (CAS CATO-C4X-2405143)
- Upadacitinib Impurity 181 (CAS CATO-C4X-2405181)
Recommended Standards
- Racecadotril Impurity 20 (CAS CATO-C4X-110620)
- 4-((1,3,3-Trimethyl-6-azabicyclo-[3.2.1]octan-6-yl)sulfonyl)benzoic acid (CAS 325830-48-6)
- 3-((1,3,3-Trimethyl-6-azabicyclo[3.2.1]Octan-6-yl)sulfonyl)benzoic acid (CAS 326182-73-4)
- 1-(4-((3-Oxocyclohex-1-en-1-yl)amino)phenyl)-3-phenylthiourea (CAS 1020252-07-6)
- Dextromethorphan Impurity 17 (CAS 30356-08-2)
- Papaverine Impurity 40 (CAS 361389-65-3)
- Tofacitinib Impurity 172 (CAS CATO-C4X-1079172)
- (7-Bromo-1,3-dioxaindan-5-yl)methanamine (CAS 1094225-67-8)
- Methyl 2-amino-3-ethoxybenzoate (CAS 1184228-27-0)
- Loxoprofen Impurity 36 (CAS 639857-67-3)
- Fmoc-Phe-Lys(Trt)-PAB (CAS 1116085-98-3)
- (3-(2-Cyanoethyl)phenyl)boronic acid (CAS 1218790-58-9)
- 7-Bromo-6-methoxybenzo[d]thiazole (CAS 1805942-09-9)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
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