Upadacitinib Impurity 150 CAS CATO-C4X-2405150
| CAS No. | CATO-C4X-2405150 |
| Molecular Formula | C8H10F3NO5S |
| Molecular Weight | 289.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
Upadacitinib Impurity 150 (CAS CATO-C4X-2405150) is a certified pharmaceutical impurity reference standard with the molecular formula C8H10F3NO5S and a molecular weight of 289.23 g/mol.
The molecular framework of Upadacitinib Impurity 150 (C8H10F3NO5S) is characterized by an amide group, a sulfone group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a certified reference material (CRM), Upadacitinib Impurity 150 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H10F3NO5S |
| Molecular Weight | 289.23 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.0 |
| UV Absorption | UV-absorbing |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 153 (CAS CATO-C4X-2405153)
- Upadacitinib Impurity 156 (CAS CATO-C4X-2405156)
- Upadacitinib Impurity 157 (CAS CATO-C4X-2405157)
- Upadacitinib Impurity 2 (CAS 1201187-46-3)
- Upadacitinib Impurity 165 (CAS CATO-C4X-2405165)
- Upadacitinib Impurity 147 (CAS CATO-C4X-2405147)
- Upadacitinib Impurity 105 (CAS CATO-C4X-2405105)
- Upadacitinib Impurity 183 (CAS 2500633-42-9)
Recommended Standards
- 4-(4-(Trifluoromethoxy)phenyl)thiazole-2-carboxylic acid (CAS 886367-05-1)
- (1-((5-Bromothiophen-2-yl)methyl)piperidin-3-yl)methanamine (CAS 1019457-89-6)
- 4-(2-Nitro-4-(trifluoromethyl)phenyl)thiazol-2-amine (CAS 256425-07-7)
- (1-{[(3,4-Dichlorophenyl)methyl]amino}-3-methylbutan-2-yl)dimethylamine (CAS 1036614-61-5)
- Cefpirome Impurity 52 (CAS CATO-C4X-120752)
- Bisoprolol EP Impurity R (CAS 5790-46-5)
- Pyridoxine Impurity 5 (CAS 4469-34-5)
- 2-Mercapto-3-methyl-6-phenyl-3H-thieno[2,3-d]pyrimidin-4-one (CAS 851398-42-0)
- 1-(5-Acetyl-1-methyl-4,5,6,7-tetrahydro-1H-pyrazolo[4,3-c]pyridine-3-carbonyl)piperidine-4-carboxylic acid (CAS 1306738-60-2)
- 3-Bromo-2-(3,3,3-trifluoropropyloxyl)benzaldehyde (CAS 1343031-21-9)
- N-(3-(2-Ethoxyethyl)benzo[d]thiazol-2(3H)-ylidene)-2-iodobenzamide (CAS 865162-48-7)
- 4,4'-Di-tert-butyl-2-nitro-1,1'-biphenyl (CAS 69386-34-1)
- 2-(4-Aminophenyl)ethanethioic S-acid (CAS 354531-38-7)
- Peptide Impurity 28 (CAS 1350456-64-2)
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