Upadacitinib Impurity 183 CAS 2500633-42-9
| CAS No. | 2500633-42-9 |
| Molecular Formula | C16H21NO4 |
| Molecular Weight | 291.34 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Upadacitinib Impurity 183 (CAS 2500633-42-9) is a certified pharmaceutical impurity reference standard with the molecular formula C16H21NO4 and a molecular weight of 291.34 g/mol.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, Upadacitinib Impurity 183 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 291.34 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Upadacitinib Impurity 183 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H21NO4 |
| Molecular Weight | 291.34 g/mol |
| Appearance | Off-white to pale yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2000 |
| Nitrogen Atoms | 1 |
Related Upadacitinib Standards
- Upadacitinib Impurity 105 (CAS CATO-C4X-2405105)
- Upadacitinib Impurity 74 (CAS 2650489-63-5)
- Upadacitinib Impurity 147 (CAS CATO-C4X-2405147)
- Upadacitinib Impurity 153 (CAS CATO-C4X-2405153)
- Upadacitinib Impurity 156 (CAS CATO-C4X-2405156)
- Upadacitinib Impurity 157 (CAS CATO-C4X-2405157)
- Upadacitinib Impurity 150 (CAS CATO-C4X-2405150)
- Upadacitinib Impurity 2 (CAS 1201187-46-3)
Recommended Standards
- Bisacodyl Impurity 9 (CAS 53555-73-0)
- Ramelteon Impurity 51 (CAS 896736-20-2)
- Bisacodyl Impurity 18 (CAS 63019-58-9)
- Naproanilide (CAS 52570-16-8)
- m-Phenylenediamine Impurity 6 (CAS CATO-C4X-34286)
- Nemonoxacin Impurity 25 (CAS 221221-15-4)
- Oseltamivir Impurity 110 (CAS CATO-C4X-1720110)
- 1-Amino-2,3-dihydro-1H-indene-4-carbonitrile (CAS 1214260-62-4)
- (S)-3-Methyl-2-(trifluoromethylsulfonamido)butanoic acid (CAS 130881-11-7)
- 1,1-Dimethoxy-2-propanamine (CAS 57390-38-2)
- 5-(Benzofuran-2-yl)-1H-indole (CAS 885273-16-5)
- 3-((Tert-butoxycarbonyl)amino)-2-(3,4-dimethoxybenzyl)propanoic acid (CAS 1260596-65-3)
- 6-(3,4-Dimethoxyphenyl)-7,7-dimethoxyoctahydroindolizine (CAS 63895-91-0)
- (9-D-Asp) Semaglutide X Sodium salt (CAS CATO-CPTD788617)
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