Lifitegrast Impurity 63 CAS CATO-C4X-240963

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-240963
Molecular FormulaC29H26N2O7S
Molecular Weight546.59 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Lifitegrast Impurity 63 CAS CATO-C4X-240963 chemical structure

Description

CATO supplies Lifitegrast Impurity 63 (CAS CATO-C4X-240963), a pharmacopoeial impurity reference standard (molecular formula C29H26N2O7S, MW 546.59 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Lifitegrast Impurity 63 (C29H26N2O7S) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC29H26N2O7S
Molecular Weight546.59 g/mol
Purity≥95%
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)18.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
Nitrogen Atoms2
Sulfur Atoms1

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