Lifitegrast Impurity 71 CAS CATO-C4X-240971
| CAS No. | CATO-C4X-240971 |
| Molecular Formula | C29H24BrClN2O7S |
| Molecular Weight | 659.93 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Lifitegrast Impurity 71 (CAS CATO-C4X-240971) is a certified pharmaceutical impurity reference standard with the molecular formula C29H24BrClN2O7S and a molecular weight of 659.93 g/mol.
Lifitegrast Impurity 71 (C29H24BrClN2O7S) contains a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine/bromine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C29H24BrClN2O7S |
| Molecular Weight | 659.93 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Lifitegrast Standards
- Lifitegrast Impurity 127 (CAS CATO-C4X-2409127)
- Lifitegrast Impurity 128 (CAS CATO-C4X-2409128)
- Lifitegrast Impurity 67 (CAS CATO-C4X-240967)
- Lifitegrast Impurity 29 (CAS CATO-C4X-240929)
- Lifitegrast Impurity 30 (CAS 1194550-61-2)
- Lifitegrast Impurity 80 (CAS CATO-C4X-240980)
- Lifitegrast impurity 95 (CAS CATO-C4X-240995)
- Lifitegrast Impurity 137 (CAS CATO-C4X-2409137)
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