Dotinurad Impurity 180 CAS CATO-C4X-2494180
| CAS No. | CATO-C4X-2494180 |
| Molecular Formula | C9H7Cl3O3 |
| Molecular Weight | 269.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a process- or degradation-related impurity, Dotinurad Impurity 180 (CAS CATO-C4X-2494180, C9H7Cl3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Dotinurad Impurity 180 (C9H7Cl3O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, chlorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by the polarity and ionization state of its functional groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures Dotinurad Impurity 180 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C9H7Cl3O3 |
| Molecular Weight | 269.51 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, ethanol, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Dotinurad Standards
- Dotinurad Impurity 57 (CAS CATO-C4X-249457)
- Dotinurad Impurity 43 (CAS CATO-C4X-249443)
- Dotinurad Impurity 120 (CAS CATO-C4X-2494120)
- Dotinurad Impurity 121 (CAS CATO-C4X-2494121)
- Dotinurad Impurity 29 (CAS CATO-C4X-249429)
- Dotinurad Impurity 103 (CAS CATO-C4X-2494103)
- Dotinurad Impurity 130 (CAS 1368227-41-1)
- Dotinurad Impurity 208 (CAS 78083-73-5)
Recommended Standards
- 926-75-0 3,5,5-Trimethyl-N-(3,5,5-trimethylhexyl)hexan-1-amine DTXSID00622569 (CAS 926-75-0)
- Benzalkonium Chloride Impurity 2 (CAS 112-69-6)
- Ethyl 4-amino-3,5,6-trichloropicolinate (CAS 91867-42-4)
- Trihexylamine (CAS 102-86-3)
- Bortezomib Impurity 5 (CAS 1132709-16-0)
- Celecoxib Impurity 12 (CAS 1061214-09-2)
- Metaraminol Impurity 79 (CAS CATO-C4X-225279)
- 3-(6,7-Dimethoxy-4-oxo-3,4-dihydroquinazolin-3-yl)propanoic acid (CAS 879319-29-6)
- 4-(1-Piperazinyl)-6-(trifluoromethyl)pyrimidine (CAS 845616-55-9)
- 2-[(3-Oxo-3,4-dihydro-2H-1,4-benzoxazin-6-yl)carbamoyl]benzoic acid (CAS 866144-71-0)
- 1-Oxa-9-thiaspiro[5.5]undecan-4-amine (CAS 1368086-72-9)
- 2-Methoxy-5-(pyrimidin-5-yl)benzaldehyde (CAS 190271-69-3)
- Gliquidone Impurity 5 (CAS 1314701-46-6)
- Tau Peptide (277-291) trifluoroacetate salt (CAS 330456-40-1)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com