Venetoclax Impurity 98 CAS CATO-C4X-249598
| CAS No. | CATO-C4X-249598 |
| Molecular Formula | C19H26Cl2N2 |
| Molecular Weight | 353.33 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
As a process- or degradation-related impurity, Venetoclax Impurity 98 (CAS CATO-C4X-249598, C19H26Cl2N2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, chlorine substitution, Venetoclax Impurity 98 is typically off-white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 353.33 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Venetoclax Impurity 98 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H26Cl2N2 |
| Molecular Weight | 353.33 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
Related Venetoclax Standards
- Venetoclax Impurity 126 (CAS CATO-C4X-2495126)
- Venetoclax Impurity 130 (CAS CATO-C4X-2495130)
- Venetoclax Impurity 97 (CAS CATO-C4X-249597)
- Venetoclax Impurity 49 (CAS CATO-C4X-249549)
- Venetoclax Impurity 52 (CAS CATO-C4X-249552)
- Venetoclax Impurity 84 (CAS CATO-C4X-249584)
- Venetoclax Impurity 79 (CAS CATO-C4X-249579)
- Venetoclax Impurity 14 (CAS CATO-C4X-249514)
Recommended Standards
- Acenocoumarol (CAS 152-72-7)
- Z-Arg(NO?)-OH (CAS 2304-98-5)
- Boc-Asn-o-nitrophenyl ester (CAS 38605-58-2)
- Roxadustat Impurity 172 (CAS CATO-C4X-2213172)
- Decitabine Impurity 37 (CAS CATO-C4X-113737)
- Iopamidol Impurity 45 (CAS CATO-C4X-145045)
- Perindopril EP Impurity L (CAS 111836-22-7)
- (2Z)-2-(Benzenesulfonyl)-3-(dimethylamino)-1-(4-methoxyphenyl)prop-2-en-1-one (CAS 344266-67-7)
- 4-Iodo-2-methyl-1-(2,2,2-trifluoroethyl)-1H-imidazole (CAS 824431-97-2)
- tert-Butyl 4-((2-chloroquinazolin-4-yl)amino)piperidine-1-carboxylate (CAS 911681-37-3)
- (2-(Trifluoromethyl)pyrimidin-4-yl)methanol (CAS 1174028-15-9)
- 1-[1-(2,4-Dimethyl-phenyl)-ethyl]-piperazine (CAS 519138-03-5)
- 2-Amino-1-naphthalenesulfonic Acid (CAS 81-16-3)
- [3-31]-Semaglutide D (CAS C152H230N42O47)
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