Venetoclax Impurity 64 CAS CATO-C4X-249564
| CAS No. | CATO-C4X-249564 |
| Molecular Formula | C46H53N7O7S |
| Molecular Weight | 848.02 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a sulfone group, a hydroxyl group, an ether linkage, Venetoclax Impurity 64 is typically pale yellow to yellow amorphous powder. Its solid-state physicochemical attributes — including a molecular weight of 848.02 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Venetoclax Impurity 64 (CAS CATO-C4X-249564) is a certified pharmaceutical impurity reference standard with the molecular formula C46H53N7O7S and a molecular weight of 848.02 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C46H53N7O7S |
| Molecular Weight | 848.02 g/mol |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 24.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
| Sulfur Atoms | 1 |
Related Venetoclax Standards
- Venetoclax Impurity 33 (CAS CATO-C4X-249533)
- Venetoclax Impurity 48 (CAS CATO-C4X-249548)
- Venetoclax Impurity 42 (CAS CATO-C4X-249542)
- Venetoclax Impurity 100 (CAS CATO-C4X-2495100)
- Venetoclax Impurity 121 (CAS CATO-C4X-2495121)
- Venetoclax Impurity 8 (CAS 2573767-91-4)
- Venetoclax Impurity 62 (CAS CATO-C4X-249562)
- Venetoclax (CAS 1257044-40-8)
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