Erdafitinib Impurity 5 CAS CATO-C4X-26165
| CAS No. | CATO-C4X-26165 |
| Molecular Formula | C26H30N6O2 |
| Molecular Weight | 458.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Erdafitinib Impurity 5 (CAS CATO-C4X-26165) is a certified pharmaceutical impurity reference standard with the molecular formula C26H30N6O2 and a molecular weight of 458.56 g/mol.
The molecular framework of Erdafitinib Impurity 5 (C26H30N6O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
As a certified reference material (CRM), Erdafitinib Impurity 5 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H30N6O2 |
| Molecular Weight | 458.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 6 |
Related Erdafitinib Standards
- Erdafitinib Impurity 6 (CAS CATO-C4X-26166)
- Erdafitinib (CAS 1346242-81-6)
- Erdafitinib Impurity 7 (CAS CATO-C4X-26167)
- Erdafitinib Impurity 11 (CAS 1346243-54-6)
- Erdafitinib Impurity 13 (CAS 1346244-83-4)
- Erdafitinib Impurity 9 (CAS CATO-C4X-26169)
- Erdafitinib Impurity 4 (CAS 2731009-66-6)
- Erdafitinib Impurity 12 (CAS CATO-C4X-261612)
Recommended Standards
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- (2E)-1-[4-(Diphenylmethyl)piperazin-1-yl]-3-[4-(3-fluoropropoxy)phenyl]prop-2-en-1-one (CAS 477871-06-0)
- Febuxostat Impurity 70 (CAS 1657014-33-9)
- Ilaprazole Impurity 127 (CAS CATO-C4X-1130127)
- Avatrombopag Impurity 108 (CAS 2489330-90-5)
- 3-Bromo-5-ethynyl-4-methylpyridine (CAS 2137782-24-0)
- N-(2-(3-Methyl-1,2,4-oxadiazol-5-yl)thiophen-3-yl)-2-(o-tolyloxy)acetamide (CAS 1796969-67-9)
- 2-Ethynyl-N-methylbenzamide (CAS 139334-73-9)
- 6-Bromo-2-naphthaldehyde (CAS 170737-46-9)
- Tetraphenylmethane (CAS 630-76-2)
- (R)-3-(Allyloxy)-2-((tert-butoxycarbonyl)amino)propanoic acid (CAS 660862-78-2)
- Semaglutide impurity 215 (CAS CATO-C4X-2226215)
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