Fluocortolone Impurity 8 CAS CATO-C4X-22308
| CAS No. | CATO-C4X-22308 |
| Molecular Formula | C27H35FO5 |
| Molecular Weight | 458.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Fluocortolone Impurity 8.
Fluocortolone Impurity 8 (CAS CATO-C4X-22308) is a certified pharmaceutical impurity reference standard with the molecular formula C27H35FO5 and a molecular weight of 458.56 g/mol.
Based on its molecular formula C27H35FO5, Fluocortolone Impurity 8 contains a steroid core, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 458.56 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Fluocortolone Impurity 8 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H35FO5 |
| Molecular Weight | 458.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Fluocortolone Standards
- Fluocortolone Impurity 6 (CAS 36130-02-6)
- Fluocortolone Impurity 9 (CAS CATO-C4X-22309)
- Fluocortolone Pivalate (CAS 29205-06-9)
- Fluocortolone Pivalate EP Impurity D (CAS CATO-C4X-223014)
- Fluocortolone Hexanoate (CAS 303-40-2)
- Fluocortolone Impurity 10 (CAS CATO-C4X-223010)
- Fluocortolone Impurity 11 (CAS CATO-C4X-223011)
- Fluocortolone Impurity 12 (CAS 66233-46-3)
Recommended Standards
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- Lexipafant (CAS 139133-26-9)
- Brexpiprazole impurity 126 (CAS CATO-C4X-1131126)
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- Citicoline Impurity 6 (CAS 52448-10-9)
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