Droperidol Impurity 18 CAS CATO-C4X-276918
| CAS No. | CATO-C4X-276918 |
| Molecular Formula | C12H12N4O2 |
| Molecular Weight | 244.25 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Droperidol Impurity 18.
As a process- or degradation-related impurity, Droperidol Impurity 18 (CAS CATO-C4X-276918, C12H12N4O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage, Droperidol Impurity 18 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 244.25 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12N4O2 |
| Molecular Weight | 244.25 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 4 |
Related Droperidol Standards
- Droperidol Impurity 12 (CAS 3308-94-9)
- Droperidol Impurity 6 (CAS 41276-30-6)
- Droperidol Impurity 16 (CAS 39146-45-7)
- Droperidol EP Impurity A (CAS 2147-83-3)
- Droperidol Impurity 13 (CAS CATO-C4X-276913)
- Droperidol Impurity 4 (CAS 25551-59-1)
- Droperidol Impurity 14 (CAS 60172-08-9)
- Droperidol Impurity 5 (CAS 65053-26-1)
Recommended Standards
- Morinidazole Impurity 4 (CAS 1415561-33-9)
- Finerenone Impurity 26 (CAS CATO-C4X-288026)
- Bumetanide Impurity 95 (CAS 688318-18-5)
- Etrasimod Impurity 48 (CAS CATO-C4X-321448)
- Dapagliflozin Impurity 125 (CAS CATO-C4X-1138125)
- Estradiol Valerate EP Impurity J (CAS CATO-C4X-28428)
- Tofacitinib Impurity 21 (CAS CATO-C4X-107921)
- 2-Isopropyl-4-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridine (CAS 1780323-05-8)
- 2-(Difluoromethyl)cyclohexan-1-one (CAS 1864054-28-3)
- Urapidil Impurity N62 (CAS 41949-07-9)
- Flurbiprofen Impurity 138 (CAS 88975-22-8)
- N-(5-Amino-2-methoxyphenyl)-2-[4-(tert-pentyl)-phenoxy]acetamide (CAS 1020055-05-3)
- (R)-2-(3-methyl-4-nitrophenyl)pyrrolidine (CAS 1389378-65-7)
- Tyr-Proinsulin C-Peptide (55-89) (human) (CAS 139532-11-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com