Droperidol Impurity 14 CAS 60172-08-9
| CAS No. | 60172-08-9 |
| Molecular Formula | C11H11N3 |
| Molecular Weight | 185.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Droperidol Impurity 14.
Droperidol Impurity 14 (CAS 60172-08-9) is a certified pharmaceutical impurity reference standard with the molecular formula C11H11N3 and a molecular weight of 185.23 g/mol.
Droperidol Impurity 14 (C11H11N3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C11H11N3 |
| Molecular Weight | 185.23 g/mol |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1974 |
| Nitrogen Atoms | 3 |
Related Droperidol Standards
- Droperidol Impurity 5 (CAS 65053-26-1)
- Droperidol Impurity 13 (CAS CATO-C4X-276913)
- Droperidol Impurity 4 (CAS 25551-59-1)
- Droperidol EP Impurity A (CAS 2147-83-3)
- Droperidol Impurity 18 (CAS CATO-C4X-276918)
- Droperidol Impurity 12 (CAS 3308-94-9)
- Droperidol Impurity 6 (CAS 41276-30-6)
- Droperidol Impurity 16 (CAS 39146-45-7)
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