Sacubitril Impurity 6 CAS CATO-C4X-28096
| CAS No. | CATO-C4X-28096 |
| Molecular Formula | 2*C24H34NO5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Sacubitril Impurity 6 (CAS CATO-C4X-28096, C24H34NO5Ca) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Sacubitril Impurity 6 (C24H34NO5Ca) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage. The carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Sacubitril Impurity 6 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | 2*C24H34NO5 Ca |
| Molecular Weight | 456.62 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 1 |
Related Sacubitril Standards
- Sacubitril impurity 41 (CAS 1038924-61-6)
- Sacubitril Impurity 5 (CAS 1038925-00-6)
- Sacubitril Lactam (CAS 1038925-22-2)
- Sacubitril impurity 50 (CAS 1039307-95-3（free base）)
- Sacubitril Sodium Salt (CAS 149690-05-1)
- Sacubitril impurity 54 (CAS 149709-63-7)
- Sacubitril Impurity 55 (CAS 149818-98-4)
- Sacubitril impurity 18 (CAS 1810778-75-6)
Recommended Standards
- Vitamin K1 Impurity 10 (CAS 132487-95-7)
- Valbenazine Impurity 6 (CAS CATO-C4X-33426)
- N-nitroso-nirogacestat impurity 1 (CAS CATO-C4X-34092)
- Ethyl 3-(isopropylcarbamoyl)-1-methyl-1h-pyrazole-5-carboxylate (CAS 957299-11-5)
- Geraniol (CAS 624-15-7)
- N-((5-((Cyanomethyl)thio)-1,3,4-oxadiazol-2-yl)methyl)-4-fluorobenzamide (CAS 872620-34-3)
- N-[4-(3-formyl-2,5-dimethyl-1h-pyrrol-1-yl)phenyl]acetamide (CAS 426217-11-0)
- 2,5-Di(furan-2-yl)thiazolo[5,4-d]thiazole (CAS 27396-05-0)
- 1-(2,4-Difluorophenyl)ethane-1-sulfonyl chloride (CAS 1248002-37-0)
- Palmitoyl Tripeptide-8 TFA salt (CAS 936544-53-5)
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