Nabumetone Impurity 24 CAS CATO-C4X-284824

Purity >95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-284824
Molecular FormulaC23H20O4
Molecular Weight360.40 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Nabumetone Impurity 24 CAS CATO-C4X-284824 chemical structure

Description

As a certified reference material (CRM), Nabumetone Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

CATO supplies Nabumetone Impurity 24 (CAS CATO-C4X-284824), a pharmacopoeial impurity reference standard (molecular formula C23H20O4, MW 360.40 g/mol) used for the identification and quantification of trace impurities in APIs.

The molecular framework of Nabumetone Impurity 24 (C23H20O4) is characterized by a flavonoid core, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

Physical & Chemical Properties

Molecular FormulaC23H20O4
Molecular Weight360.40 g/mol
AppearancePale yellow to yellow crystalline powder
Purity>95%
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present

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