Indometacin Impurity 41 CAS CATO-C4X-147041
| CAS No. | CATO-C4X-147041 |
| Molecular Formula | C25H28ClNO10 |
| Molecular Weight | 537.94 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 537.94 g/mol gives Indometacin Impurity 41 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Indometacin Impurity 41 (CAS CATO-C4X-147041) is a certified pharmaceutical impurity reference standard with the molecular formula C25H28ClNO10 and a molecular weight of 537.94 g/mol.
Structurally, Indometacin Impurity 41 (C25H28ClNO10) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 537.94 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C25H28ClNO10 |
| Molecular Weight | 537.94 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Indometacin Standards
- Indometacin Impurity 44 (CAS CATO-C4X-147044)
- Indometacin Impurity 42 (CAS CATO-C4X-147042)
- Indometacin Farnesil (CAS 85801-02-1)
- Indometacin Impurity 28 (CAS 193603-94-0)
- Indometacin Impurity 37 (CAS CATO-C4X-147037)
- Indometacin Impurity 38 (CAS CATO-C4X-147038)
- Indometacin Impurity 43 (CAS CATO-C4X-147043)
- Indometacin EP Impurity J (CAS 402849-25-6)
Recommended Standards
- Methyl 2-[2-({4-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]piperazin-1-yl}sulfonyl)-4,5-dimethoxyphenyl]acetate (CAS 1024415-60-8)
- C16-Ceramide (CAS 24696-26-2)
- Gadolinium(III) iodide (CAS 13572-98-0)
- 477243-06-4 C16 Ceramide Ceramide (Egg) Ceramide (Egg, Chicken) N-(hexadecanoyl)-sphing-4-enine N-hexadecanoyl-D-erythro-sphingosine (CAS 477243-06-4)
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- Letermovir Impurity 80 (CAS CATO-C4X-291580)
- Cephalexin Impurity 28 (CAS 142975-48-2)
- 1-(4-Fluorophenyl)cyclohexanecarboxylic Acid (CAS 214263-00-0)
- 4-(2-Methoxyphenyl)-1H-1,2,3-triazole (CAS 369363-77-9)
- N-((1-(sec-Butyl)-1H-pyrazol-5-yl)methyl)propan-1-amine hydrochloride (CAS 1856078-81-3)
- Chlorphenamine Impurity 69 (CAS CATO-C4X-118869)
- Hexahydro-3H-oxazolo[3,4-a]pyrazin-3-one (CAS 937047-42-2)
- n1-Cyclopropyl-n3,n3-dimethylpropane-1,3-diamine (CAS 1184082-71-0)
- β-Bag Cell Peptide (Aplysia californica) (CAS 109024-47-7)
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