Cabotegravir Impurity 24 CAS CATO-C4X-287624
| CAS No. | CATO-C4X-287624 |
| Molecular Formula | C21H17F5N2 |
| Molecular Weight | 392.37 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Cabotegravir Impurity 24.
CATO supplies Cabotegravir Impurity 24 (CAS CATO-C4X-287624), a pharmacopoeial impurity reference standard (molecular formula C21H17F5N2, MW 392.37 g/mol) used for the identification and quantification of trace impurities in APIs.
Cabotegravir Impurity 24 (C21H17F5N2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Cabotegravir Impurity 24 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H17F5N2 |
| Molecular Weight | 392.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Cabotegravir Standards
- Cabotegravir Impurity 2 (CAS CATO-C4X-28762)
- Cabotegravir (CAS 1051375-10-0)
- Cabotegravir Impurity 11 (CAS 1646862-08-9)
- Cabotegravir Impurity 13 (CAS CATO-C4X-287613)
- Cabotegravir Impurity 16 (CAS 2883234-39-5)
- Cabotegravir Impurity 9 (CAS CATO-C4X-28769)
- Cabotegravir Impurity 12 (CAS CATO-C4X-287612)
- Cabotegravir Impurity 10 (CAS CATO-C4X-287610)
Recommended Standards
- 5-Bromo-7-(5,5,7,7-tetramethyloctan-3-yl)quinolin-8-ol (CAS 60877-72-7)
- 2,2-Dimethyl-1,3-dioxolane-4-methanol Dibenzyl Phosphate (CAS 13879-76-0)
- 2,6-Diphenyl-3-(3-(trifluoromethyl)phenyl)pyrimidin-4(3H)-one (CAS 89069-88-5)
- Decernotinib (CAS 944842-54-0)
- Lemborexant Impurity 48 (CAS CATO-C4X-304248)
- N-Nitroso Levetiracetam Impurity 39 (CAS CATO-C4X-106739)
- Tofacitinib Impurity 32 (CAS CATO-C4X-107932)
- 4-(3-Methylbutyl)-5-(phenoxymethyl)-4h-1,2,4-triazole-3-thiol (CAS 854035-84-0)
- Palbociclib Impurity 118 (CAS 844843-37-4)
- N’-hydroxy-2,3-dihydro-1,4-benzodioxine-2-carboximidamide (CAS 85084-37-3)
- Tert-butyl 4-ethyl-3-hydroxypiperidine-1-carboxylate (CAS 1188264-81-4)
- (4-(4-Aminophenyl)piperazin-1-yl)(p-tolyl)methanone (CAS 262376-01-2)
- 2-(2-Methyl-5-(1H-tetrazol-1-yl)phenoxy)acetic acid (CAS 924859-17-6)
- Stresscopin-Related Peptide (human) (CAS 348626-74-4)
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