Vericiguat Impurity 32 CAS CATO-C4X-289632
| CAS No. | CATO-C4X-289632 |
| Molecular Formula | C25H21F2N9O2 |
| Molecular Weight | 517.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Vericiguat Impurity 32 (CAS CATO-C4X-289632) is a certified pharmaceutical impurity reference standard with the molecular formula C25H21F2N9O2 and a molecular weight of 517.49 g/mol.
Structurally, Vericiguat Impurity 32 (C25H21F2N9O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 19.0, corresponding to approximately 19 ring(s) or double-bond equivalent(s). With a molecular weight of 517.49 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C25H21F2N9O2 |
| Molecular Weight | 517.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 9 |
Related Vericiguat Standards
- Vericiguat Impurity 8 (CAS CATO-C4X-28968)
- Vericiguat Impurity 20 (CAS CATO-C4X-289620)
- Vericiguat Impurity 34 (CAS CATO-C4X-289634)
- Vericiguat Impurity 7 (CAS CATO-C4X-28967)
- Vericiguat impurity 51 (CAS CATO-C4X-289651)
- Vericiguat impurity 50 (CAS CATO-C4X-289650)
- Vericiguat impurity 55 (CAS CATO-C4X-289655)
- Vericiguat Impurity 6 (CAS CATO-C4X-28966)
Recommended Standards
- 9,10-Dihydro-9,10-bis(2-carboxyethyl)-N-(4-nitrophenyl)-10,9-(epoxyimino)anthracene-12-carboxamide (CAS 1225023-87-9)
- Ethyl 2-(diisobutoxyphosphoryl)-3,3,3-trifluoro-2-((4-methylphenyl)sulfonamido)propanoate (CAS 255872-07-2)
- (2R,3S,4R,5R)-5-azido-2-((benzoyloxy)methyl)-6-hydroxytetrahydro-2H-pyran-3,4-diyl dibenzoate (CAS 1003221-97-3)
- Vonoprazan Impurity 166 (CAS CATO-C4X-1020166)
- Trazodone impurity 49 (CAS CATO-C4X-177249)
- Lasmiditan Impurity 37 HBr (CAS 1338000-32-0)
- Olaparib Impurity 101 (CAS CATO-C4X-1135101)
- (5-Ethyl-8-oxo-5,8-dihydro-[1,3]dioxolo[4,5-g]quinoline-7-carbonyl)-L-alanine (CAS 79721-05-4)
- 5-Chloro-2-ethoxyphenol (CAS 57428-47-4)
- 2-Amino-N-butylbenzenesulfonamide (CAS 436095-51-1)
- Methyl 1-oxo-1,2-dihydroisoquinoline-5-carboxylate (CAS 91137-50-7)
- 4-Bromo-1-(difluoromethyl)-3-((2,2,2-trifluoroethoxy)methyl)-1H-pyrazole (CAS 1856026-08-8)
- 1-chloro-2-(chloromethyl)-4-nitrobenzene (CAS 69422-57-7)
- Insulin Degludec Impurity 16 (CAS CATO-C4X-215716)
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