Resmetirom impurity 103 CAS CATO-C4X-2912103
| CAS No. | CATO-C4X-2912103 |
| Molecular Formula | C13H12Cl3N3O |
| Molecular Weight | 332.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Resmetirom impurity 103 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
As a process- or degradation-related impurity, Resmetirom impurity 103 (CAS CATO-C4X-2912103, C13H12Cl3N3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Resmetirom impurity 103 (C13H12Cl3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C13H12Cl3N3O |
| Molecular Weight | 332.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Resmetirom Standards
- Resmetirom Impurity 30 (CAS CATO-C4X-291230)
- Resmetirom Impurity 5 (CAS 920509-27-9)
- Resmetirom impurity 68 (CAS CATO-C4X-291268)
- Resmetirom impurity 69 (CAS CATO-C4X-291269)
- Resmetirom Impurity 50 (CAS CATO-C4X-291250)
- Resmetirom Impurity 102 (CAS CATO-C4X-2912102)
- Resmetirom Impurity 48 (CAS CATO-C4X-291248)
- Resmetirom impurity 108 (CAS CATO-C4X-2912108)
Recommended Standards
- N-(2-Chloro-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridin-3-yl)methanesulfonamide (CAS 1204742-83-5)
- N-(methylsulfonyl)-N-(2,4,5-trichlorophenyl)glycine (CAS 714260-75-0)
- 3,4-Dichloro-N-(4-chloro-5-cyanothiazol-2-yl)benzamide (CAS 866154-04-3)
- Dodecyltriethoxysilane (CAS 18536-91-9)
- Azilsartan Impurity 63 (CAS 985638-55-8)
- Saxagliptin Impurity 8 (CAS 1445592-86-8)
- Chlorpheniramine Impurity 38 (CAS CATO-C4X-118838)
- 3-Methylcyclobutanamine (CAS 89381-06-6)
- Dapagliflozin Impurity 132 (CAS CATO-C4X-1138132)
- 1-tert-Butyl 5-methyl 2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-1,5-dicarboxylate (CAS 1956380-20-3)
- 5-(Tert-butyl)-3-chloro-2-hydroxybenzaldehyde (CAS 71730-43-3)
- Amoroven EP impurity L TFA Salt (CAS CATO-C4X-154222)
- Methyl 5-((2-fluorophenyl)ethynyl)-furan-2-carboxylate (CAS 725228-58-0)
- Semaglutide impurity 74 (CAS CATO-C4X-222674)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com