Resmetirom impurity 69 CAS CATO-C4X-291269
| CAS No. | CATO-C4X-291269 |
| Molecular Formula | C13H12Cl3N3O |
| Molecular Weight | 332.61 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Resmetirom impurity 69 (C13H12Cl3N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Resmetirom impurity 69 (CAS CATO-C4X-291269, C13H12Cl3N3O) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Resmetirom impurity 69 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H12Cl3N3O |
| Molecular Weight | 332.61 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Resmetirom Standards
- Resmetirom impurity 103 (CAS CATO-C4X-2912103)
- Resmetirom Impurity 30 (CAS CATO-C4X-291230)
- Resmetirom Impurity 5 (CAS 920509-27-9)
- Resmetirom impurity 68 (CAS CATO-C4X-291268)
- Resmetirom Impurity 50 (CAS CATO-C4X-291250)
- Resmetirom Impurity 102 (CAS CATO-C4X-2912102)
- Resmetirom Impurity 48 (CAS CATO-C4X-291248)
- Resmetirom impurity 108 (CAS CATO-C4X-2912108)
Recommended Standards
- 6-Bromo-4-chloro-8-methyl-2-phenylquinoline (CAS 1155601-60-7)
- 8-Bromo-4-chloro-6-methyl-2-phenylquinoline (CAS 1156275-50-1)
- (5-Bromo-2-chlorophenyl)(4-methoxypiperidin-1-yl)methanone (CAS 1183379-23-8)
- 4-Bromo-8-chloro-6-methyl-2-phenylquinoline (CAS 1189106-11-3)
- Cefotiam Impurity 3 (CAS CATO-C4X-12043)
- Ofloxacin EP Impurity E (CAS 82419-52-1)
- Hydroxychloroquine Impurity 77 (CAS CATO-C4X-183577)
- Butyl({[3-(trifluoromethyl)phenyl]methyl})amine (CAS 90390-09-3)
- Ganirelix (CAS 124904-93-4)
- 3,7-Dimethyl-1-octanol (CAS 106-21-8)
- 6-Isopropoxybenzo[d][1,3]dioxol-5-amine (CAS 1312698-41-1)
- 2-(2,5-Dioxotetrahydrofuran-3-yl)acetic acid (CAS 4756-10-9)
- 2-(2,3-dihydro-1-benzofuran-5-yl)-1H-imidazole (CAS 1378826-21-1)
- Semaglutide impound 212 (CAS CATO-C4X-2226212)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com