Resmetirom Impurity 48 CAS CATO-C4X-291248
| CAS No. | CATO-C4X-291248 |
| Molecular Formula | C13H14Cl3N3O |
| Molecular Weight | 334.63 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Resmetirom Impurity 48 (CAS CATO-C4X-291248), a pharmacopoeial impurity reference standard (molecular formula C13H14Cl3N3O, MW 334.63 g/mol) used for the identification and quantification of trace impurities in APIs.
Resmetirom Impurity 48 (C13H14Cl3N3O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H14Cl3N3O |
| Molecular Weight | 334.63 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 7.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Resmetirom Standards
- Resmetirom Impurity 102 (CAS CATO-C4X-2912102)
- Resmetirom impurity 103 (CAS CATO-C4X-2912103)
- Resmetirom Impurity 30 (CAS CATO-C4X-291230)
- Resmetirom Impurity 5 (CAS 920509-27-9)
- Resmetirom impurity 68 (CAS CATO-C4X-291268)
- Resmetirom impurity 69 (CAS CATO-C4X-291269)
- Resmetirom Impurity 50 (CAS CATO-C4X-291250)
- Resmetirom impurity 108 (CAS CATO-C4X-2912108)
Recommended Standards
- (3-Acryloxypropyl)methylbis(trimethylsiloxy)-silane (CAS 177617-17-3)
- 4-(3-(2-Bromo-4-chlorophenoxy)propyl)morpholine (CAS 1002540-31-9)
- 5-Bromo-N-(1-(5-chlorothiophen-2-yl)ethyl)furan-2-carboxamide (CAS 1147744-30-6)
- 1-(2-(4-Bromo-2-chlorophenoxy)ethyl)piperidin-4-ol (CAS 1704074-59-8)
- Afoxolaner Impurity 14 (CAS 1125726-30-8)
- Cefamandole EP Impurity C (CAS 36922-15-3)
- Ticagrelor Nitroso EP Impurity B (CAS CATO-C4X-1093164)
- N-[(6-methylpyridin-3-yl)methyl]cyclopropanamine (CAS 1094655-05-6)
- 4-Bromo-pyrimidine-2-carbonitrile (CAS 1160995-48-1)
- 6-Methyl-5-phenylpyridazin-3-amine (CAS 105537-98-2)
- 4-(3-Chlorophenoxy)benzaldehyde (CAS 164522-90-1)
- 1-Fluoro-2-(prop-2-en-1-yloxy)benzene (CAS 57264-49-0)
- 7-Bromo-8-methyl-2-propylquinolin-4-amine (CAS 1189105-52-9)
- Des-[Oct-γ-Glu-AEEA-AEEA]-Semaglutide (CAS CATO-C4X-2226112)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com