Resmetirom impurity 123 CAS CATO-C4X-2912123
| CAS No. | CATO-C4X-2912123 |
| Molecular Formula | C26H23Cl4N5O4 |
| Molecular Weight | 611.30 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Resmetirom impurity 123 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Resmetirom impurity 123 (CAS CATO-C4X-2912123) is a certified pharmaceutical impurity reference standard with the molecular formula C26H23Cl4N5O4 and a molecular weight of 611.30 g/mol.
Resmetirom impurity 123 (C26H23Cl4N5O4) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C26H23Cl4N5O4 |
| Molecular Weight | 611.30 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 5 |
Related Resmetirom Standards
- Resmetirom impurity 107 (CAS CATO-C4X-2912107)
- Resmetirom impurity 118 (CAS CATO-C4X-2912118)
- Resmetirom impurity 106 (CAS CATO-C4X-2912106)
- Resmetirom impurity 119 (CAS CATO-C4X-2912119)
- Resmetirom Impurity 11 (CAS CATO-C4X-291211)
- Resmetirom impurity 88 (CAS CATO-C4X-291288)
- Resmetirom Impurity 97 (CAS CATO-C4X-291297)
- Resmetirom impurity 105 (CAS CATO-C4X-2912105)
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- Varenicline Impurity 16 (CAS 1337563-47-9)
- 5,6-Difluoro-1,2,3,4-tetrahydronaphthalen-1-amine (CAS 907973-48-2)
- Ethyl 3-(benzyloxy)-5-bromo-1-methyl-2-oxo-1,2-dihydropyridine-4-carboxylate (CAS 2387599-96-2)
- 2-{2-[2-(4-chlorophenyl)adamantan-2-yl]acetamido}ethyl N-phenylcarbamate (CAS 400085-12-3)
- 2-(Methylthio)pyridin-3-amine (CAS 38240-22-1)
- (S)-2-((1-methylpiperidin-3-yl)oxy)acetic acid (CAS 1354002-21-3)
- n3,n3-Dimethylpyridine-2,3-diamine (CAS 50426-30-7)
- Gastric Inhibitory Polypeptide (3-42) (human) trifluoroacetate salt (CAS 1802086-25-4)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com