Abemaciclib Impurity 129 CAS CATO-C4X-2937129

Purity ≥95%In StockPharmacopoeial Impurity Standards
CAS No.CATO-C4X-2937129
Molecular FormulaC18H36N4Si2
Molecular Weight364.68 g/mol
CategoryPharmacopoeial Impurity Standards / EP Impurities
AvailabilityIn Stock

Chemical Structure

Abemaciclib Impurity 129 CAS CATO-C4X-2937129 chemical structure

Description

CATO supplies Abemaciclib Impurity 129 (CAS CATO-C4X-2937129), a pharmacopoeial impurity reference standard (molecular formula C18H36N4Si2, MW 364.68 g/mol) used for the identification and quantification of trace impurities in APIs.

Owing to a nitrile group, Abemaciclib Impurity 129 is typically white to pale yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 364.68 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.

CATO manufactures Abemaciclib Impurity 129 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H36N4Si2
Molecular Weight364.68 g/mol
AppearanceWhite to pale yellow crystalline powder
Purity≥95%
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityLight-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)3.0
UV AbsorptionUV-absorbing
Nitrogen Atoms4

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