Abemaciclib Impurity 3 CAS CATO-C4X-29373
| CAS No. | CATO-C4X-29373 |
| Molecular Formula | C22H24F2N4 |
| Molecular Weight | 382.45 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Abemaciclib Impurity 3 (CAS CATO-C4X-29373) is a certified pharmaceutical impurity reference standard with the molecular formula C22H24F2N4 and a molecular weight of 382.45 g/mol.
Structurally, Abemaciclib Impurity 3 (C22H24F2N4) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 382.45 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Abemaciclib Impurity 3 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H24F2N4 |
| Molecular Weight | 382.45 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
Related Abemaciclib Standards
- Abemaciclib Impurity 160 (CAS CATO-C4X-2937160)
- Abemaciclib impurity 112 (CAS CATO-C4X-2937112)
- Abemaciclib Impurity 184 (CAS CATO-C4X-2937184)
- Abemaciclib Impurity 153 (CAS CATO-C4X-2937153)
- Abemaciclib Impurity 182 (CAS CATO-C4X-2937182)
- Abemaciclib Impurity 183 (CAS CATO-C4X-2937183)
- Abemaciclib Impurity 85 (CAS CATO-C4X-293785)
- Abemaciclib Impurity 161 (CAS CATO-C4X-2937161)
Recommended Standards
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- T2 toxin Triol (CAS 34114-98-2)
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- Isocorynoxeine (CAS 51014-29-0)
- Domperidone Impurity 24 (CAS 99-54-7)
- Iopromide Impurity 27 (CAS CATO-C4X-183227)
- Iloprost Impurity 6 (CAS CATO-C4X-32026)
- N-[(1S,2S)-1,2,3,4-Tetrahydro-1-hydroxy-7-methoxy-2-naphthalenyl]-chloroacetamide (CAS 99833-89-3)
- Ferimzone (CAS 89269-64-7)
- Cinacalcet Impurity 101 (CAS CATO-C4X-1059101)
- (-)-Ilaprazole (CAS 834897-64-2)
- (S)-2-(Ethyl(1-methylpiperidin-3-yl)amino)acetic acid (CAS 1354008-21-1)
- 2-(4-Formyl-2-methoxyphenoxy)-N-phenethylacetamide (CAS 832674-36-9)
- Semaglutide（sodium salt） (CAS CATO-C4X-222619)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com