Belumosudil Impurity 28 CAS CATO-C4X-298828
| CAS No. | CATO-C4X-298828 |
| Molecular Formula | C26H23N7O3 |
| Molecular Weight | 481.51 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Belumosudil Impurity 28 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Belumosudil Impurity 28 (CAS CATO-C4X-298828, C26H23N7O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Belumosudil Impurity 28 (C26H23N7O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Belumosudil Impurity 28 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C26H23N7O3 |
| Molecular Weight | 481.51 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 19.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Belumosudil Standards
- Belumosudil Impurity 15 (CAS CATO-C4X-298815)
- Belumosudil Impurity 25 (CAS CATO-C4X-298825)
- Belumosudil Impurity 54 (CAS CATO-C4X-298854)
- Belumosudil Impurity 51 (CAS CATO-C4X-298851)
- Belumosudil Impurity 36 (CAS CATO-C4X-298836)
- Belumosudil Impurity 23 (CAS CATO-C4X-298823)
- Belumosudil-d7 (CAS CATO-C4X-298826)
- Belumosudil Impurity 42 (CAS CATO-C4X-298842)
Recommended Standards
- (R)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(sulfomethyl)phenyl)propanoic acid (CAS 206060-44-8)
- (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-(sulfomethyl)phenyl)propanoic acid (CAS 206060-45-9)
- Methotrexate Dimethylamide (CAS 71074-44-7)
- 2-(2-(Diphenylphosphino)phenyl)-4,5-diphenyloxazole (CAS 2757082-54-3)
- Rosuvastatin Impurity 154 (CAS 154026-94-5)
- Diclofenac Impurity 44 (CAS 69002-85-3)
- Ticagrelor Impurity 186 (CAS CATO-C4X-1093186)
- 3-Methoxybenzofuran (CAS 63923-68-2)
- 2-(4-Benzylpiperazin-1-yl)thiazole-5-carbaldehyde (CAS 303987-22-6)
- Phthalic Acid (CAS 88-99-3)
- (1-(Pyridin-3-yl)-1H-imidazol-4-yl)methanamine (CAS 1427011-27-5)
- 4-(tert-Butoxycarbonyl)-3-chlorobenzoic acid (CAS 431888-59-4)
- 2-((Allyloxy)methyl)-4-fluorobenzenethiol (CAS 1378574-86-7)
- Peptide Impurity 24 (CAS CATO-CPTD788824)
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