Lemborexant Impurity 90 CAS CATO-C4X-304290
| CAS No. | CATO-C4X-304290 |
| Molecular Formula | C11H13FO2 |
| Molecular Weight | 196.22 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Lemborexant Impurity 90 (C11H13FO2) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine substitution, an aromatic ring system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Lemborexant Impurity 90 (CAS CATO-C4X-304290) is a certified pharmaceutical impurity reference standard with the molecular formula C11H13FO2 and a molecular weight of 196.22 g/mol.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Lemborexant Impurity 90 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C11H13FO2 |
| Molecular Weight | 196.22 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor) |
| Purity | ≥95% |
| Storage | Store at 2-8°C, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 5.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
Related Lemborexant Standards
- Lemborexant Impurity 52 (CAS CATO-C4X-304252)
- Lemborexant Impurity 85 (CAS CATO-C4X-304285)
- Lemborexant impurity 1 (CAS 73781-88-1)
- Lemborexant Impurity 45 (CAS CATO-C4X-304245)
- Lemborexant impurity 3 (CAS 571189-49-6)
- Lemborexant impurity 4 (CAS 528587-70-4)
- Lemborexant Impurity 53 (CAS CATO-C4X-304253)
- Lemborexant Impurity 61 (CAS 528587-69-1)
Recommended Standards
- 5-(1-Ethyl-1h-pyrazol-4-yl)-1,3,4-oxadiazole-2-thiol (CAS 1004643-47-3)
- 5-((3-Methyl-1h-pyrazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol (CAS 1004643-57-5)
- Safinamide Impurity 23 (CAS CATO-C4X-159023)
- 5-((5-Methyl-1h-pyrazol-1-yl)methyl)-1,3,4-oxadiazole-2-thiol (CAS 1004644-22-7)
- Indacaterol Impurity 48 (CAS 1384189-12-1)
- Hydrocortisone Impurity 01 (CAS 10215-75-5)
- Amorolfine EP Impurity E HCl (trans-Amorolfine HCl) (Mixture of Diastereomers) (CAS CATO-C4X-154212)
- (1-(4-Chloro-3-(trifluoromethyl)phenyl)-1H-1,2,3-triazol-4-yl)methanol (CAS 1267621-74-8)
- Methyl 2-bromo-4,5-dichlorobenzoate (CAS 2091686-17-6)
- 4-(3-fluorophenyl)-2-methylbutanoic acid (CAS 1354950-70-1)
- 5-methoxy-3,4-dihydro-2H-1-benzopyran-3-one (CAS 109140-20-7)
- (E)-N'-((1-(4-chlorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl)methylene)thiophene-3-carbohydrazide (CAS 866042-24-2)
- Eltrombopag Impurity 135 (CAS CATO-C4X-1198135)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
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