Binimetinib Impurity 7 CAS CATO-C4X-30507
| CAS No. | CATO-C4X-30507 |
| Molecular Formula | C19H19BrF2N4O3 |
| Molecular Weight | 469.28 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO supplies Binimetinib Impurity 7 (CAS CATO-C4X-30507), a pharmacopoeial impurity reference standard (molecular formula C19H19BrF2N4O3, MW 469.28 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Binimetinib Impurity 7 (C19H19BrF2N4O3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 11.0, corresponding to approximately 11 ring(s) or double-bond equivalent(s). With a molecular weight of 469.28 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a certified reference material (CRM), Binimetinib Impurity 7 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H19BrF2N4O3 |
| Molecular Weight | 469.28 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Br-containing |
| Nitrogen Atoms | 4 |
Related Binimetinib Standards
- Binimetinib Impurity 2 (CAS CATO-C4X-30502)
- Binimetinib Impurity N1 (CAS 1415559-75-9)
- Binimetinib Impurity 6 (CAS CATO-C4X-30506)
- Binimetinib Impurity 4 (CAS CATO-C4X-30504)
- Binimetinib-D3 (CAS CATO-C4X-30508)
- Binimetinib (CAS 606143-89-9)
- Binimetinib Amide Impurity (CAS 1604812-70-5)
- Binimetinib Impurity 3 (CAS CATO-C4X-30503)
Recommended Standards
- 3,7-Dibromo-10-(2-ethylhexyl)-10H-phenothiazine (CAS 264263-98-1)
- 2-((5-((2,4-Dichlorophenoxy)methyl)-1,3,4-oxadiazol-2-yl)thio)-N-(3-nitrophenyl)propanamide (CAS 332114-40-6)
- 2-((2-(4-Bromophenyl)-2-oxoethyl)thio)-3-phenyl-6-(trifluoromethyl)pyrimidin-4(3H)-one (CAS 692287-52-8)
- 1-(2,4-Dichloro-5-methoxyphenyl)-5-methyl-N-(4-phenoxyphenyl)-1H-1,2,4-triazole-3-carboxamide (CAS 339015-16-6)
- Sildenafil Impurity 101 (CAS CATO-C4X-1128101)
- Apalutamide Impurity 28 (CAS CATO-C4X-274928)
- Glipizide Impurity 25 (CAS CATO-C4X-140725)
- 2-Bromo-7-fluorotricyclo[6.2.0.03,6]deca-1,3(6),7-triene (CAS 2676868-20-3)
- 2-Azaspiro[3.3]heptan-6-one (CAS 1700611-14-8)
- Mirogabalin Impurity 18 (CAS 1138245-49-4)
- Methyl 2-amino-3-((1-methyl-1h-tetrazol-5-yl)thio)butanoate (CAS 1706431-29-9)
- 4-Ethoxy-2-(trifluoromethyl)pyrimidine (CAS 24903-68-2)
- 79002-45-2 {[(benzyloxy)carbonyl]amino}(hydroxy)acetic acid (CAS 79002-45-2)
- 107444-51-9 0JS9125PIZ Glucagon-like peptide 1 (7-36) Glucagon-related peptide 1 (Rana catesbeiana), 3-L-glutamic acid-10-L-valine-16-glycine-17-L-glutamine-23-L-isoleucine-24-L-alanine-27-L-valine-30-L-argininamide-31-de-L-proline-32-de-L-lysine- Glp-I (7-36) Proglucagon (78-107) Human glucagon-like peptide-1-(7-36) amide Human GLP-1-(7-36)-amide Glucagon-like peptide-I(7-36) amide Rat GLP-I(7-36)amide Insulinotropin (human) MKC 253 UNII-0JS9125PIZ (CAS 107444-51-9)
Why CATO?
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