Acalabrutinib Impurity 19 CAS CATO-C4X-305519
| CAS No. | CATO-C4X-305519 |
| Molecular Formula | C24H23N7O2 |
| Molecular Weight | 441.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO supplies Acalabrutinib Impurity 19 (CAS CATO-C4X-305519), a pharmacopoeial impurity reference standard (molecular formula C24H23N7O2, MW 441.49 g/mol) used for the identification and quantification of trace impurities in APIs.
Structurally, Acalabrutinib Impurity 19 (C24H23N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 441.49 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Acalabrutinib Impurity 19 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23N7O2 |
| Molecular Weight | 441.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Acalabrutinib Standards
- Acalabrutinib Impurity 18 (CAS CATO-C4X-305518)
- Acalabrutinib Impurity 23 (CAS CATO-C4X-305523)
- Acalabrutinib Impurity 13 (CAS CATO-C4X-305513)
- Acalabrutinib Impurity N1 (CAS 1952316-43-6)
- Acalabrutinib (CAS 1420477-60-6)
- Acalabrutinib Impurity 22 (CAS CATO-C4X-305522)
- Acalabrutinib Impurity 2 (CAS CATO-C4X-30552)
- Acalabrutinib Impurity 3 (CAS CATO-C4X-30553)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com