Acalabrutinib Impurity 23 CAS CATO-C4X-305523
| CAS No. | CATO-C4X-305523 |
| Molecular Formula | C24H23N7O2 |
| Molecular Weight | 441.49 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Structurally, Acalabrutinib Impurity 23 (C24H23N7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage. The molecule exhibits a degree of unsaturation (DBE) of 17.0, corresponding to approximately 17 ring(s) or double-bond equivalent(s). With a molecular weight of 441.49 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
As a process- or degradation-related impurity, Acalabrutinib Impurity 23 (CAS CATO-C4X-305523, C24H23N7O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Acalabrutinib Impurity 23 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H23N7O2 |
| Molecular Weight | 441.49 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 17.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 7 |
Related Acalabrutinib Standards
- Acalabrutinib Impurity 18 (CAS CATO-C4X-305518)
- Acalabrutinib Impurity 19 (CAS CATO-C4X-305519)
- Acalabrutinib Impurity 13 (CAS CATO-C4X-305513)
- Acalabrutinib Impurity N1 (CAS 1952316-43-6)
- Acalabrutinib (CAS 1420477-60-6)
- Acalabrutinib Impurity 22 (CAS CATO-C4X-305522)
- Acalabrutinib Impurity 2 (CAS CATO-C4X-30552)
- Acalabrutinib Impurity 3 (CAS CATO-C4X-30553)
Recommended Standards
- Nafcillin-d5 Sodium Salt (CAS 1356354-25-0)
- N-(6-Amino-1-(2-methoxyethyl)-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-5-yl)-N-benzyl-2-(methylthio)nicotinamide (CAS 1012508-42-7)
- Ravuconazole Impurity 1 (CAS 1329499-27-5)
- N-(4-(N-(3-(6-Oxo-3-(pyridin-4-yl)pyridazin-1(6H)-yl)propyl)sulfamoyl)phenyl)propionamide (CAS 1021072-39-8)
- Guaiazulene Impurity 8 (CAS CATO-C4X-22378)
- Ampicillin Impurity 20 (CAS CATO-C4X-144320)
- Etoposide EP Impurity B (CAS 100007-56-5)
- N-(2-(2-bromoethoxy)phenyl)acetamide (CAS 119416-25-0)
- 3-(4-Fluorophenyl)oxazolidin-2-one (CAS 353265-73-3)
- (R)-3-(2-Methoxyphenyl)morpholine (CAS 1213498-30-6)
- 2-(1-Methylhydrazinyl)-3-(trifluoromethyl)pyridine (CAS 175205-68-2)
- 1-(4-Methoxythiophen-2-yl)ethan-1-one (CAS 34694-78-5)
- N,N'-Bis[4-di(m-tolyl)aminophenyl]-N,N'-diphenylbenzidine (CAS 199121-98-7)
- Semaglutide impurity 271 (CAS CATO-C4X-2226271)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com