Darolutamide impurity 7 CAS CATO-C4X-31067
| CAS No. | CATO-C4X-31067 |
| Molecular Formula | C21H23ClN6O2 |
| Molecular Weight | 426.90 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Darolutamide impurity 7 is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Darolutamide impurity 7 (CAS CATO-C4X-31067, C21H23ClN6O2) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Darolutamide impurity 7 (C21H23ClN6O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Darolutamide impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H23ClN6O2 |
| Molecular Weight | 426.90 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 6 |
Related Darolutamide Standards
- Darolutamide Impurity 17 (CAS CATO-C4X-310617)
- Darolutamide Impurity 21 (CAS CATO-C4X-310621)
- Darolutamide impurity 5 (CAS CATO-C4X-31065)
- Darolutamide Impurity 47 (CAS CATO-C4X-310647)
- Darolutamide Impurity 18 (CAS CATO-C4X-310618)
- Darolutamide impurity 6 (CAS CATO-C4X-31066)
- Darolutamide Impurity 34 (CAS CATO-C4X-310634)
- Darolutamide Impurity 28 (CAS CATO-C4X-310628)
Recommended Standards
- (Z)-Methyl 2-(1-(2-chlorophenyl)-4-((3-(dimethylamino)phenyl)(methylamino)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl)acetate (CAS 1820587-57-2)
- Halometasone impurity 14 (CAS CATO-C4X-144614)
- 3-[1-(5-Chloro-2-methoxybenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775513-33-1)
- Fluticasone Impurity 101 (CAS CATO-C4X-1650101)
- Eravacycline impurity 13 (CAS CATO-C4X-293813)
- Ciclosporin Impurity 17 (CAS CATO-C4X-199817)
- Torasemide Impurity 13 (CAS CATO-C4X-183613)
- Tetrakis(diethylamino)vanadium(IV), min. 95% TDEAV (CAS 219852-96-7)
- 1-Butyl-1-methylpyrrolidinium Dicyanamide (CAS 370865-80-8)
- Semaglutide Impurity 138 (CAS CATO-C4X-2226138)
- S-Ethyl 2-(5-ethoxytetrahydrofuran-2-yl)ethanethioate (CAS 475275-15-1)
- 4-Aminopicolinimidamide (CAS 1342267-80-4)
- Pentyl 2-(3-oxopiperazin-2-yl)acetate (CAS 1025736-40-6)
- Antistasin-Related Peptide (CAS 161561-46-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com