Fluticasone Impurity 101 CAS CATO-C4X-1650101
| CAS No. | CATO-C4X-1650101 |
| Molecular Formula | C22H28ClFO5 |
| Molecular Weight | 426.91 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Fluticasone Impurity 101 is closely related to a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Fluticasone Impurity 101 (CAS CATO-C4X-1650101), a pharmacopoeial impurity reference standard (molecular formula C22H28ClFO5, MW 426.91 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C22H28ClFO5, Fluticasone Impurity 101 contains a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 426.91 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Fluticasone Impurity 101 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28ClFO5 |
| Molecular Weight | 426.91 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Fluticasone Standards
- Fluticasone Impurity 49 (CAS CATO-C4X-165049)
- Fluticasone Impurity 68 (CAS 1744-64-5)
- Fluticasone Furoate Impurity 2 (CAS 1355648-15-5)
- Fluticasone Impurity 106 (CAS CATO-C4X-1650106)
- Fluticasone Impurity 111 (CAS 785806-92-0)
- Fluticasone Impurity 112 (CAS CATO-C4X-1650112)
- Fluticasone Impurity 54 (CAS 4571-51-1)
- Fluticasone Impurity 96 (CAS CATO-C4X-165096)
Recommended Standards
- Halometasone impurity 14 (CAS CATO-C4X-144614)
- Darolutamide impurity 7 (CAS CATO-C4X-31067)
- (Z)-Methyl 2-(1-(2-chlorophenyl)-4-((3-(dimethylamino)phenyl)(methylamino)methylene)-5-oxo-4,5-dihydro-1H-pyrazol-3-yl)acetate (CAS 1820587-57-2)
- 3-[1-(5-Chloro-2-methoxybenzoyl)piperidin-4-yl]-4-(4-methylphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775513-33-1)
- Rivastigmine Impurity 41 (CAS CATO-C4X-138441)
- Tolvaptan Impurity 36 (CAS CATO-C4X-195536)
- Ensifentrine impurity 12 (CAS CATO-C4X-335312)
- 1-(Bromomethyl)-3-chloro-5-fluorobenzene (CAS 493024-39-8)
- 3,5-dibromo-4-(triphenylmethyl)-4H-1,2,4-Triazole (CAS 1398511-24-4)
- (1-(4-(Trifluoromethyl)pyrimidin-2-yl)piperidin-3-yl)methanol (CAS 916791-20-3)
- [1-(3-Bromo-benzenesulfonyl)-piperidin-4-yl]-methyl-amine hydrochloride (CAS 1353986-07-8)
- 4-cyclohexylbenzohydrazide (CAS 179166-82-6)
- N-(2-fluoro-3-methoxyphenyl)thietan-3-amine (CAS 1881369-12-5)
- Semaglutide Impurity 186 (CAS CATO-C4X-2226186)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com