Teriflunomide impurity 2 CAS CATO-C4X-31202
| CAS No. | CATO-C4X-31202 |
| Molecular Formula | C13H11F3N2O2 |
| Molecular Weight | 284.23 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Teriflunomide impurity 2 (CAS CATO-C4X-31202) is a certified pharmaceutical impurity reference standard with the molecular formula C13H11F3N2O2 and a molecular weight of 284.23 g/mol.
The molecular framework of Teriflunomide impurity 2 (C13H11F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
CATO manufactures Teriflunomide impurity 2 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C13H11F3N2O2 |
| Molecular Weight | 284.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Teriflunomide Standards
- Teriflunomide Impurity C53 (CAS 1011244-72-6)
- (E)-Teriflunomide (CAS 214782-56-6)
- Teriflunomide Impurity 5 (CAS 220512-86-7)
- Teriflunomide Impurity 6 (CAS 62004-05-1)
- Teriflunomide impurity 1 (CAS CATO-C4X-31201)
- Teriflunomide Impurity 2 (CAS 69066-42-8)
- Teriflunomide Impurity 7 (CAS 854677-43-3)
- Teriflunomide Impurity 4 (CAS CATO-C4X-31204)
Recommended Standards
- Elagolix Impurity 79 (CAS CATO-C4X-206879)
- Xanthosine (CAS 146-80-5)
- Regadenoson Impurity 50 (CAS CATO-C4X-198550)
- 1-{5-methyl-1-[5-(trifluoromethyl)pyridin-2-yl]-1H-pyrazol-4-yl}ethanone oxime (CAS 1019075-45-6)
- Goserelin BP Impurity 5 Acetate (CAS CATO-C4X-192035)
- Foscarnet Sodium EP Impurity A (CAS 72305-00-1)
- Carbocisteine Impurity 36 (CAS CATO-C4X-201036)
- 3,5-Dimethylbenzamide (CAS 5692-35-3)
- Tert-butyl 3-((2-methoxyethyl)amino)piperidine-1-carboxylate (CAS 887588-09-2)
- N-(2-Methoxyphenyl)-2-[2-(trifluoromethyl)-1H-1,3-benzodiazol-1-yl]acetamide (CAS 478042-47-6)
- tert-Butyl 4-(1-(3-(((4-methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)carbamoyl)-2-methyl-1H-indol-1-yl)ethyl)piperidine-1-carboxylate (CAS 1450655-10-3)
- Lead tungstate (CAS 7759-01-5)
- (4-Methyl-1H-indol-5-yl)methanamine (CAS 1369368-84-2)
- Osteogenic Growth Peptide (CAS 132996-61-3)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com