Teriflunomide Impurity 7 CAS 854677-43-3
| CAS No. | 854677-43-3 |
| Molecular Formula | C9H6F3NO2 |
| Molecular Weight | 217.14 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Teriflunomide Impurity 7 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Teriflunomide Impurity 7 (CAS 854677-43-3) is a certified pharmaceutical impurity reference standard with the molecular formula C9H6F3NO2 and a molecular weight of 217.14 g/mol.
The molecular framework of Teriflunomide Impurity 7 (C9H6F3NO2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C9H6F3NO2 |
| Molecular Weight | 217.14 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Teriflunomide Standards
- Teriflunomide Impurity 4 (CAS CATO-C4X-31204)
- Teriflunomide Impurity 2 (CAS 69066-42-8)
- (E)-Teriflunomide (CAS 214782-56-6)
- Teriflunomide Impurity 5 (CAS 220512-86-7)
- Teriflunomide Impurity 6 (CAS 62004-05-1)
- Teriflunomide Impurity C53 (CAS 1011244-72-6)
- Teriflunomide impurity 2 (CAS CATO-C4X-31202)
- Teriflunomide impurity 1 (CAS CATO-C4X-31201)
Recommended Standards
- (E)-3-[6-(trifluoromethyl)-3-pyridinyl]-2-propenoic acid (E)-3-[6-(trifluoromethyl)pyridin-3-yl]prop-2-enoic acid 773131-93-4 A839038 (CAS 773131-93-4)
- Flurofamide (CAS 70788-28-2)
- Methyl 5-Nitrouracil-6-carboxylate (CAS 6311-73-5)
- (E)-1-(2-Nitrovinyl)-3-(Trifluoromethyl)Benzene (CAS 115665-96-8)
- Xanomeline impurity 50 (CAS CATO-C4X-330150)
- Empagliflozin Impuirity 141 (CAS CATO-C4X-1065141)
- Vinpocetine Impurity 4 (CAS 27773-65-5)
- 2-(Dipropylamino)acetonitrile (CAS 18071-35-7)
- 2-(2,4-Difluorophenoxy)-4,8-dimethylquinoline (CAS 478032-29-0)
- N-Phenyltetrafluorophthalimide (CAS 116508-58-8)
- 2-Chloro-5,6-dibromobenzo[d]thiazole, 97% (CAS 1209460-20-7)
- 2-Bromo-1-(3-fluoropyridin-4-yl)ethan-1-one hydrobromide (CAS 845538-59-2)
- 2-((5-(2-Methoxyphenyl)-4-methyl-4H-1,2,4-triazol-3-yl)thio)acetic acid (CAS 333312-58-6)
- Semaglutide Impurity 2 (CAS CATO-C4X-22262)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com