Afoxolaner Impurity 11 CAS CATO-C4X-313711
| CAS No. | CATO-C4X-313711 |
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of Afoxolaner Impurity 11 (C14H12O3) is characterized by a carboxylic acid group, a hydroxyl group, an ether linkage, a polycyclic aromatic system. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Afoxolaner Impurity 11 (CAS CATO-C4X-313711) is a certified pharmaceutical impurity reference standard with the molecular formula C14H12O3 and a molecular weight of 228.24 g/mol.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Afoxolaner Impurity 11 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C14H12O3 |
| Molecular Weight | 228.24 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
Related Afoxolaner Standards
- Afoxolaner Impurity 27 (CAS 2382920-55-8)
- Afoxolaner impurity 2 (CAS CATO-C4X-31372)
- Afoxolaner Impurity 26 (CAS CATO-C4X-313726)
- Afoxolaner Impurity 10 (CAS CATO-C4X-313710)
- Afoxolaner Impurity 33 (CAS CATO-C4X-313733)
- Afoxolaner impurity 11 (CAS CATO-C4X-31381)
- Afoxolaner impurity 3 (CAS CATO-C4X-31373)
- Afoxolaner Impurity 1 (CAS 1125812-54-5)
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