Dapoxetine Impurity 52 CAS 1445281-25-3
| CAS No. | 1445281-25-3 |
| Molecular Formula | C19H17ClO |
| Molecular Weight | 296.79 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Dapoxetine Impurity 52.
CATO supplies Dapoxetine Impurity 52 (CAS 1445281-25-3), a pharmacopoeial impurity reference standard (molecular formula C19H17ClO, MW 296.79 g/mol) used for the identification and quantification of trace impurities in APIs.
Dapoxetine Impurity 52 (C19H17ClO) contains a steroid core, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H17ClO |
| Molecular Weight | 296.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | >90% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1992 |
| Halogen Content | Cl-containing |
Related Dapoxetine Standards
- Dapoxetine Impurity 40 (CAS CATO-C4X-143940)
- Dapoxetine Impurity 32 (CAS CATO-C4X-143932)
- Dapoxetine Impurity 26 (CAS 147199-39-1)
- Dapoxetine N-Desmethyl (CAS 119357-18-5)
- Dapoxetine RC 2 (CAS 1776071-89-6)
- Dapoxetine Impurity 92 (CAS CATO-C4X-143992)
- Dapoxetine Impurity 88 (CAS CATO-C4X-143988)
- Dapoxetine Impurity 102 (CAS 119356-77-3)
Recommended Standards
- Pentoxyverine Impurity 14 (CAS CATO-C4X-227014)
- α-1,2,3,4,5,6-Hexachlorocyclohexane-13C6 (CAS 222966-66-7)
- Carebastine Impurity 5 (CAS CATO-C4X-31695)
- tert-Butyl 3-(4-chlorophenyl)piperazine-1-carboxylate (CAS 886767-49-3)
- Tiotropium impurity 48 (CAS CATO-C4X-176448)
- Topiroxostat Impurity 62 (CAS CATO-C4X-105562)
- Baloxavir Marboxil Impurity 211 (CAS CATO-C4X-2108211)
- (R)-O-(2-(4-Chlorophenoxy)propyl)hydroxylamine hydrochloride (CAS 1956437-19-6)
- 2-Chloro-N'-[6-chloro-4-(trifluoromethyl)pyridin-2-yl]benzene-1-sulfonohydrazide (CAS 1790211-83-4)
- 5-(3-Fluorophenyl)-2-methylaniline (CAS 1183439-66-8)
- 4-Amino-5-benzoylisoxazole-3-carboxamide (CAS 76390-64-2)
- 4-Bromo-2-(methoxymethyl)pyridine (CAS 864412-04-4)
- (2S,4S)-2-Amino-4-butylpentanedioicacid (CAS 1217602-18-0)
- Semaglutide Impurity 21(HO-Ste-L-γGlu-AEEA-AEEA-OH) (CAS 1335440-44-2)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com