Etrasimod Impurity 68 CAS CATO-C4X-321468
| CAS No. | CATO-C4X-321468 |
| Molecular Formula | C28H28F3NO3 |
| Molecular Weight | 483.52 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Etrasimod Impurity 68.
As a process- or degradation-related impurity, Etrasimod Impurity 68 (CAS CATO-C4X-321468, C28H28F3NO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
The molecular framework of Etrasimod Impurity 68 (C28H28F3NO3) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Etrasimod Impurity 68 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C28H28F3NO3 |
| Molecular Weight | 483.52 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | ≥95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 14.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related Etrasimod Standards
- Etrasimod impurity 21 (CAS CATO-C4X-321421)
- Etrasimod Impurity 62 (CAS 3053992-15-4)
- Etrasimod Impurity 12 (CAS CATO-C4X-321412)
- Etrasimod impurity 3 (CAS CATO-C4X-32143)
- Etrasimod Impurity 60 (CAS CATO-C4X-321460)
- Etrasimod Impurity 52 (CAS CATO-C4X-321452)
- Etrasimod Impurity 53 (CAS CATO-C4X-321453)
- Etrasimod impurity 18 (CAS CATO-C4X-321418)
Recommended Standards
- Vazegepant Impurity 16 (CAS CATO-C4X-320016)
- (4AR,6S,7R,8R,8aS)-7-(1,3-dioxoisoindolin-2-yl)-6-(ethylthio)-2-phenylhexahydropyrano[3,2-d][1,3]dioxin-8-yl acetate (CAS 125520-04-9)
- Acalabrutinib Impurity 1 (CAS CATO-C4X-30551)
- Ethyl 2-(2-((3-cyano-6-methyl-4-(trifluoromethyl)pyridin-2-yl)thio)acetamido)-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylate (CAS 445383-14-2)
- Isoprenaline Impurity 19 (CAS CATO-C4X-277519)
- Lusutrombopag Impurity 20 (CAS 30279-00-6)
- Clindamycin Impurity 99 (CAS CATO-C4X-134199)
- 3H-Indolium, 2-[2-[2-chloro-3-[2-[1,3-dihydro- 3,3-dimethyl-1-(4-sulfobutyl)-2H-indol-2- ylidene]ethylidene]-1-cyclohexen-1-yl]ethenyl]- 3,3-dimethyl-1-(4-sulfobutyl)-, inner salt, 97% (CAS 162411-20-3)
- Fenoterol Impurity 6 (CAS CATO-C4X-20776)
- 2-(4-Methoxyphenyl)-5-(4-nitrophenyl)-1,3,4-oxadiazole (CAS 62507-51-1)
- n-(2-(5-Methoxy-1h-indol-3-yl)ethyl)pyrimidin-2-amine (CAS 866038-50-8)
- (Z)-10-Tetradecenyl Acetate (CAS 35153-16-3)
- Palbociclib Impurity 187 (CAS CATO-C4X-1125187)
- Myristoyl Pentapeptide-4 (CAS 1392416-25-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com