Orforglipron Impurity 137 CAS CATO-C4X-3234137
| CAS No. | CATO-C4X-3234137 |
| Molecular Formula | C31H34FN7O3 |
| Molecular Weight | 571.65 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 571.65 g/mol gives Orforglipron Impurity 137 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Orforglipron Impurity 137 (CAS CATO-C4X-3234137, C31H34FN7O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Orforglipron Impurity 137 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 571.65 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C31H34FN7O3 |
| Molecular Weight | 571.65 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 7 |
Related Orforglipron Standards
- Orforglipron impurity 119 (CAS CATO-C4X-3234119)
- Orforglipron Impurity 3 (CAS 2212022-55-2)
- Orforglipron impurity 74 (CAS CATO-C4X-323474)
- Orforglipron Impurity 85 (CAS CATO-C4X-323485)
- Orforglipron Impurity 37 (CAS 2923760-40-9)
- Orforglipron impurity 130 (CAS CATO-C4X-3234130)
- Orforglipron impurity 102 (CAS 3047292-99-6)
- Orforglipron Impurity 103 (CAS CATO-C4X-3234103)
Recommended Standards
- Omadacycline Impurity 25 (CAS CATO-C4X-285725)
- Azide-PEG12-alcohol (CAS 1821464-55-4)
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- Osimertinib Impurity 108 (CAS CATO-C4X-2045108)
- Posaconazole Impurity 118 (CAS 81445-45-6)
- Pefloxacin Impurity 8 (CAS CATO-C4X-23338)
- Oxibendazole Impurity 2 (CAS 20367-33-3)
- 4-(Trifluoromethoxy)phenylhydrazine Hydrochloride (CAS 133115-72-7)
- 1-Methyl-4,5,9,10-tetrahydropyrene (CAS 102251-78-5)
- Sacubitril impurity 47 (CAS CATO-C4X-280947)
- 6-Fluoro-4-hydroxyquinoline-7-carbonitrile (CAS 1260761-66-7)
- 5-Bromo-2-(1-isopropyl-1H-pyrazol-4-yl)pyridine (CAS 1394022-29-7)
- Etofenprox-(<I>ethoxy</I>-d<SUB>5</SUB>) (CAS 1705649-55-3)
- Hexapeptide-11 (CAS 161258-30-6)
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