HISTIDINE Impurity 13 CAS CATO-C4X-323913
| CAS No. | CATO-C4X-323913 |
| Molecular Formula | C8H13N3O2 |
| Molecular Weight | 183.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including HISTIDINE Impurity 13.
CATO supplies HISTIDINE Impurity 13 (CAS CATO-C4X-323913), a pharmacopoeial impurity reference standard (molecular formula C8H13N3O2, MW 183.21 g/mol) used for the identification and quantification of trace impurities in APIs.
The molecular framework of HISTIDINE Impurity 13 (C8H13N3O2) is characterized by an amino-acid-derived structure, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), HISTIDINE Impurity 13 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C8H13N3O2 |
| Molecular Weight | 183.21 g/mol |
| Appearance | Off-white to pale yellow crystalline powder. (faint amine-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 4.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 3 |
Related HISTIDINE Standards
- HISTIDINE Impurity 8 (CAS CATO-C4X-32398)
- HISTIDINE Impurity 9 (CAS CATO-C4X-32399)
- HISTIDINE Impurity 12 (CAS CATO-C4X-323912)
- HISTIDINE impurity 3 (CAS CATO-C4X-32393)
- HISTIDINE Impurity 6 (CAS 1932060-69-9)
- D-Histidine Methyl Ester (CAS 17720-12-6)
- HISTIDINE Impurity N1 (CAS CATO-C1416939)
- L-Histidine, N,N-dimethyl-, sodium salt (1:1) (CAS 2703746-04-5)
Recommended Standards
- Epalrestat impurity 32 (CAS CATO-C4X-223632)
- Phenoxazine (CAS 135-67-1)
- Pranoprofen Impurity 36 (CAS 261-27-8)
- 2-Amino-9H-pyrido[2,3-b]indole (CAS 26148-68-5)
- Lidocaine Impurity 39 (CAS 77966-82-6)
- Dotinurad Impurity 143 (CAS CATO-C4X-2494143)
- Vinorelbine Impurity 19 (CAS CATO-C4X-264219)
- 3-(Aminomethyl)-1-isobutyl-6-methylpyridin-2(1H)-one (CAS 1267221-21-5)
- 5-Ethynyl-2-fluoro-4-methylpyridine (CAS 1824459-89-3)
- Methyl 5-(((tert-butoxycarbonyl)amino)methyl)-2-(difluoromethyl)benzoate (CAS 1381846-31-6)
- N-[(4-Chlorophenyl)methyl]-2-(3,5-dimethylphenoxy)-N-(2-methoxyethyl)acetamide (CAS 866043-10-9)
- [1-[[(3R)-3-fluoropyrrolidin-1-yl]methyl]cyclopropyl]methanol (CAS 2561517-87-9)
- Benzyl (((S)-1-((S)-2-aminopropanoyl)pyrrolidin-2-yl)methyl)(ethyl)carbamate (CAS 1401669-11-1)
- Semaglutide impurity 227 (CAS CATO-C4X-2226227)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com