Encorafenib Impurity 12 CAS CATO-C4X-32412
| CAS No. | CATO-C4X-32412 |
| Molecular Formula | C6H6BClFNO2 |
| Molecular Weight | 189.38 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Encorafenib Impurity 12.
Encorafenib Impurity 12 (CAS CATO-C4X-32412) is a certified pharmaceutical impurity reference standard with the molecular formula C6H6BClFNO2 and a molecular weight of 189.38 g/mol.
Based on its molecular formula C6H6BClFNO2, Encorafenib Impurity 12 contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 189.38 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Encorafenib Impurity 12 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C6H6BClFNO2 |
| Molecular Weight | 189.38 g/mol |
| Appearance | White to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 3.5 |
| UV Absorption | UV-absorbing |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Encorafenib Standards
- Encorafenib Impurity 7 (CAS 2285221-21-6)
- Encorafenib Impurity 11 (CAS CATO-C4X-324911)
- Encorafenib Impurity 6 (CAS CATO-C4X-32496)
- Encorafenib Impurity 8 (CAS CATO-C4X-32498)
- Encorafenib Impurity 15 (CAS CATO-C4X-324915)
- Encorafenib Impurity 9 (CAS CATO-C4X-32499)
- Encorafenib Impurity 13 (CAS CATO-C4X-324913)
- Encorafenib Impurity 11 (CAS CATO-C4X-32411)
Recommended Standards
- Hexylmagnesium Bromide (20% in Tetrahydrofuran, ca. 1mol/L) (CAS 3761-92-0)
- 1,3-Diethyl-1,1,3,3-tetramethyldisilazane (CAS 17882-94-9)
- 3-Hexylmagnesium bromide (CAS 68941-76-4)
- Zinc oxalate dihydrate (CAS 55906-21-3)
- Ceftiofur Impurity 7 (CAS CATO-C4X-15817)
- Pinaverium Bromide Impurity 20 (CAS CATO-C4X-246720)
- Loxoprofen Impurity 139 (CAS CATO-C4X-1488139)
- N-Methyl-D-alanyl-4-fluoro-D-phenylalanine phenylmethyl ester hydrochloride (CAS 874336-39-7)
- 3-(2-Fluorophenyl)-2-methylpropanoic acid (CAS 943113-85-7)
- 4-(5-Bromo-2-fluorophenyl)-4-cyclopropyloxazolidin-2-one (CAS 1266784-58-0)
- N-Methoxy-N-methyl-5,6,7,8-tetrahydro-1-naphthalenecarboxamide (CAS 185957-97-5)
- 4-Iodo-1-naphthonitrile (CAS 140456-96-8)
- Triphenylphosphine(2,5-norbornadiene)rhodium(I) tetrafluoroborate (CAS 305367-01-5)
- Tirzepatide Impurity 24 X TFA Salt (CAS CATO-C4X-324024)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com