Encorafenib Impurity 11 CAS CATO-C4X-32411
| CAS No. | CATO-C4X-32411 |
| Molecular Formula | C21H25ClFN7O2 |
| Molecular Weight | 461.92 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
CATO manufactures Encorafenib Impurity 11 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
CATO supplies Encorafenib Impurity 11 (CAS CATO-C4X-32411), a pharmacopoeial impurity reference standard (molecular formula C21H25ClFN7O2, MW 461.92 g/mol) used for the identification and quantification of trace impurities in APIs.
Encorafenib Impurity 11 (C21H25ClFN7O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
Physical & Chemical Properties
| Molecular Formula | C21H25ClFN7O2 |
| Molecular Weight | 461.92 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 7 |
Related Encorafenib Standards
- Encorafenib Impurity 10 (CAS 1269440-78-9)
- Encorafenib Impurity 18 (CAS CATO-C4X-324918)
- Encorafenib Impurity 13 (CAS CATO-C4X-324913)
- Encorafenib Impurity 15 (CAS CATO-C4X-324915)
- Encorafenib Impurity 9 (CAS CATO-C4X-32499)
- Encorafenib Impurity 3 (CAS CATO-C4X-32493)
- Encorafenib Impurity 8 (CAS CATO-C4X-32498)
- Encorafenib Impurity 12 (CAS CATO-C4X-324912)
Recommended Standards
- Ticagrelor Impurity 116 (CAS 1863036-47-8)
- N'-[(1E)-{3-[(2-chloro-1,3-thiazol-5-yl)methoxy]phenyl}methylidene]-3,4,5-trimethoxybenzohydrazide (CAS 477886-84-3)
- 4-[(5E)-5-[(4-Chloro-3-nitrophenyl)methylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]-4-azatricyclo[5.2.1.0^{2,6}]dec-8-ene-3,5-dione (CAS 477766-88-4)
- 1-((4-(Tert-butyl)phenyl)sulfonyl)-4-(3-chloro-5-(trifluoromethyl)pyridin-2-yl)piperazine (CAS 260368-22-7)
- Fingolimod EP Impurity I (CAS 249289-10-9)
- Atenolol Impurity 12 (CAS 35198-42-6)
- Indocyanine Green Impurity 43 (CAS CATO-C4X-250343)
- 2-[(methoxycarbonyl)amino]-2-methylpropanoic acid (CAS 91826-96-9)
- 1-Methoxy-6-nitro-1H-benzo[d]imidazole (CAS 24246-33-1)
- N-(3-(2-Phenylmorpholino)propyl)-4-propylbenzamide (CAS 953915-25-8)
- 2-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-2-(4-chlorophenyl)-N-((4-chlorophenyl)carbamoyl)acetamide (CAS 262439-69-0)
- (S)-2-Amino-3-(2-(bis(2-chloroethyl)amino)phenyl)propanoic acid (CAS 342-95-0)
- 2-(Aminomethyl)-6-(difluoromethyl)pyridin-4-amine (CAS 1805030-40-3)
- Peptide 433 (CAS CATO-CPTD788433)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com