Anlotinib Impurity 3 CAS CATO-C4X-32833
| CAS No. | CATO-C4X-32833 |
| Molecular Formula | C30H28FN3O3 |
| Molecular Weight | 497.56 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 497.56 g/mol gives Anlotinib Impurity 3 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
As a process- or degradation-related impurity, Anlotinib Impurity 3 (CAS CATO-C4X-32833, C30H28FN3O3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution, Anlotinib Impurity 3 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 497.56 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Anlotinib Impurity 3 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C30H28FN3O3 |
| Molecular Weight | 497.56 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 18.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related Anlotinib Standards
Recommended Standards
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- 5-Aminothiazolo[4,5-d]pyrimidine-2,7(3H,6H)-dione (CAS 30161-97-8)
- Lubiprostone impurity 7 (CAS CATO-C4X-11367)
- 9-(Biphenyl-4-yl)carbazole-2-boronic acid (CAS 1686100-04-8)
- 2-[(2R,6S)-2,6-Dimethylmorpholin-4-yl]pyridin-3-amine (CAS 1602566-65-3)
- tert-Butyl (S)-2-(2,2,2-trifluoroethyl)piperazine-1-carboxylate (CAS 1240582-25-5)
- Hexapeptide-1 (CAS CATO-CPTD788821)
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