Atrasentan Impurity 208 CAS CATO-C4X-3347208
| CAS No. | CATO-C4X-3347208 |
| Molecular Formula | C12H22BrNO3 |
| Molecular Weight | 308.21 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Atrasentan Impurity 208 is closely related to an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
As a process- or degradation-related impurity, Atrasentan Impurity 208 (CAS CATO-C4X-3347208, C12H22BrNO3) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Structurally, Atrasentan Impurity 208 (C12H22BrNO3) contains an amide group, a carboxylic acid group, a hydroxyl group, an ether linkage, bromine substitution. The molecule exhibits a degree of unsaturation (DBE) of 2.0, corresponding to approximately 2 ring(s) or double-bond equivalent(s). With a molecular weight of 308.21 g/mol, it falls into the moderately-high-molecular-weight range. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a certified reference material (CRM), Atrasentan Impurity 208 meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H22BrNO3 |
| Molecular Weight | 308.21 g/mol |
| Purity | ≥95% |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 2.0 |
| Halogen Content | Br-containing |
| Nitrogen Atoms | 1 |
Related Atrasentan Standards
- Atrasentan Impurity 210 (CAS CATO-C4X-3347210)
- Atrasentan Impurity 4 (CAS CATO-C4X-33474)
- Atrasentan Impurity 186 (CAS CATO-C4X-3347186)
- Atrasentan Impurity 187(2S,3S,4S) (CAS CATO-C4X-3347187)
- Atrasentan Impurity 188 (CAS CATO-C4X-3347188)
- Atrasentan Impurity 189 (CAS CATO-C4X-3347189)
- Atrasentan Impurity 190 (CAS CATO-C4X-3347190)
- Atrasentan Impurity 191 (CAS CATO-C4X-3347191)
Recommended Standards
- Tert-butyl 3-(2-bromoethyl)-3-ethoxyazetidine-1-carboxylate (CAS 2306275-23-8)
- 4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1-naphthoic acid (CAS 1073353-77-1)
- Tert-butyl (S)-6-(bromomethyl)-2,2-dimethylmorpholine-4-carboxylate (CAS 2375249-44-6)
- 1260675-56-6 2-Bromo-6-(4-(dimethylamino)-piperidin-1-yl)benzonitrile (CAS 1260675-56-6)
- Latanoprost Impurity 26 (CAS CATO-C4X-194126)
- Bendamustine Impurity 6 (CAS CATO-C4X-12716)
- Varenicline Impurity 12 (CAS CATO-C4X-196212)
- 4-Ethynyl-2,5-difluoropyridine (CAS 1426243-94-8)
- (5R,7S)-7-methyl-2,8-diazaspiro[4.5]Decan-3-one (CAS 1246650-85-0)
- 6-Chloro-N-(3-methoxypropyl)-2-pyridinamine (CAS 29449-81-8)
- Oxazolo[4,5-b]pyridin-2(3H)-one (CAS 60832-72-6)
- 4-Ethoxypyrrolo[1,2-b]pyridazine-3-carboxylic acid (CAS 156335-40-9)
- Tofacitinib Impurity 173 (CAS CATO-C4X-1079173)
- Semaglutide impurity 01 (CAS 1998701-31-7)
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