Acemetacin EP Impurity C CAS CATO-C4X-33821
| CAS No. | CATO-C4X-33821 |
| Molecular Formula | C21H17Cl2NO6 |
| Molecular Weight | 450.27 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Acemetacin EP Impurity C (C21H17Cl2NO6) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
CATO supplies Acemetacin EP Impurity C (CAS CATO-C4X-33821), a pharmacopoeial impurity reference standard (molecular formula C21H17Cl2NO6, MW 450.27 g/mol) used for the identification and quantification of trace impurities in APIs.
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
CATO manufactures Acemetacin EP Impurity C under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H17Cl2NO6 |
| Molecular Weight | 450.27 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Acemetacin Standards
- Acemetacin EP Impurity D (CAS 76812-64-1)
- Acemetacin EP Impurity E (CAS 75302-98-6)
- Acemetacin EP Impurity F (CAS 76812-49-2)
- Acemetacin-D4 (CAS 1196151-16-2)
- Acemetacin (CAS 53164-05-9)
- Acemetacin acyl-β-D-glucuronide (CAS 1260603-31-3)
- Acemetacin Impurity 1 (CAS 77914-62-6)
- Acemetacin EP Impurity B Potassium Salt (CAS 28751-45-3)
Recommended Standards
- tert-Butyl 6-(benzyloxy)-3-iodo-1H-indazole-1-carboxylate (CAS 944904-61-4)
- 2-(6-Bromo-4-oxoquinazolin-3(4H)-yl)-N-(4-phenoxyphenyl)acetamide (CAS 853318-75-9)
- Ethyl 2-(3-(2-(2-(2,4-dichlorophenoxy)acetyl)hydrazono)-2-oxoindolin-1-yl)acetate (CAS 444771-51-1)
- 5-(3-Bromophenyl)-5,11-dihydro-1,3-dimethyl-1H-indeno[2′,1′:5,6]pyrido[2,3-d]pyrimidine-2,4,6(3H)-trione (CAS 325746-94-9)
- Tazobactam Impurity 19 (CAS CATO-C4X-120519)
- Tofacitinib Impurity 148 (CAS CATO-C4X-1079148)
- Etoricoxib impurity 64 (CAS 65719-09-7)
- 6-Phenyl-2-(propylthio)pyrimidin-4(1H)-one (CAS 62459-13-6)
- 2,4-Bis(trichloromethyl)-4H-benzo[d][1,3]dioxine-6-sulfonyl chloride (CAS 61720-32-9)
- 2-Octylfuran (CAS 4179-38-8)
- 2-Amino-6,7-dimethoxyquinoline-3-carboxamide (CAS 55149-43-4)
- (2S)-2-acetamido-3-(3-phenoxyphenyl)propanoic acid (CAS 1384435-43-1)
- 3-Chloro-6,8-difluoro-2H-benzo[e][1,2,4]thiadiazine 1,1-dioxide (CAS 1437434-20-2)
- Serpent Peptide (CAS 823202-99-9)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
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