Clobetasol 17-Propionate-d5 CAS CATO-CCAD302397
| CAS No. | CATO-CCAD302397 |
| Molecular Formula | - |
| Molecular Weight | 472.00 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of Clobetasol 17-Propionate-d5 is closely related to deuterium isotope labeling, a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
CATO supplies Clobetasol 17-Propionate-d5 (CAS CATO-CCAD302397), a certified reference material (molecular formula C25H27D5ClFO5, MW 472.00 g/mol) for analytical method development and quality control.
Owing to deuterium isotope labeling, a flavonoid core, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, Clobetasol 17-Propionate-d5 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 472.00 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures Clobetasol 17-Propionate-d5 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H27D5ClFO5 |
| Molecular Weight | 472.00 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.5 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | F/Cl-containing |
Related Clobetasol Standards
- Clobetasol Propionate EP Impurity D (CAS 25120-99-4)
- Clobetasol Propionate EP Impurity C (CAS 25122-52-5)
- Clobetasol Propionate (CAS 25122-46-7)
- Clobetasol butyrate (CAS 25122-47-8)
- Clobetasol Propionate Impurity (21-Chloro-16β-methyl-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione) (CAS 95796-50-2)
- Clobetasol Propionate EP Impurity J (CAS 1486466-31-2)
- Clobetasol Propionate Impurity 19 (CAS CATO-C4X-159219)
- Clobetasol Propionate EP Impurity A (CAS 5534-13-4)
Recommended Standards
- 4-((4-Chlorophenyl)thio)-1-(4-methoxyphenyl)-2-phenyl-6,7-dihydro-1H-indole-5-carbaldehyde (CAS 477869-19-5)
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- 4-((2-Chlorophenyl)thio)-1-(4-methoxyphenyl)-2-phenyl-6,7-dihydro-1H-indole-5-carbaldehyde (CAS 477887-77-7)
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- 2-(4-Cyano-3-hydroxy-5-methylphenyl)acetic acid (CAS 1806267-04-8)
- Jacaranone (CAS 60263-07-2)
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Why CATO?
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