Hydrocortisone Impurity 75 CAS 220489-73-6
| CAS No. | 220489-73-6 |
| Molecular Formula | C25H34O8 |
| Molecular Weight | 462.53 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Hydrocortisone Impurity 75.
CATO supplies Hydrocortisone Impurity 75 (CAS 220489-73-6), a pharmacopoeial impurity reference standard (molecular formula C25H34O8, MW 462.53 g/mol) used for the identification and quantification of trace impurities in APIs.
Based on its molecular formula C25H34O8, Hydrocortisone Impurity 75 contains a flavonoid core, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 462.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Hydrocortisone Impurity 75 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C25H34O8 |
| Molecular Weight | 462.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2019 |
Related Hydrocortisone Standards
- Hydrocortisone Impurity 32 (CAS 103242-89-3)
- Hydrocortisone Impurity 67 (CAS 146201-55-0)
- Hydrocortisone 21-Hemisuccinate (CAS 2203-97-6)
- Hydrocortisone Impurity 39 (CAS 3593-96-2)
- Hydrocortisone 17-Propionate 21-Acetate (CAS 74050-20-7)
- Hydrocortisone Impurity 01 (CAS 10215-75-5)
- Hydrocortisone impurity 40 (CAS 33767-18-9)
- Hydrocortisone Impurity 60 (CAS CATO-C4X-140160)
Recommended Standards
- 6-[N,N-Di(2-hydroxybenzyl)amino]-2-[(3-hydroxypropyl)amino]-9-isopropylpurine (CAS 1076200-04-8)
- Canagliflozin Impurity 87 (CAS CATO-C4X-112387)
- 1132816-77-3 tert-Butyl 3-[1-methyl-3-(4-benzyl-2-oxo-1,3-oxazol-idin-3-yl)-3-oxopropyl]indole-1-carboxylate (CAS 1132816-77-3)
- Canagliflozin Impurity 8(1S,2S,3R,4R,5S) (CAS CATO-C4X-11238)
- Olopatadine Impurity 11 (CAS 56427-76-0)
- Cefotiam Impurity 40 (CAS CATO-C4X-120440)
- Lovastatin Impurity N1 (CAS 106909-04-0)
- 5-(1-Methylhydrazin-1-yl)-4-phenyl-1,2,3-thiadiazole (CAS 866136-25-6)
- 3,3'-Bis(allyloxy)-[1,1'-biphenyl]-4,4'-diamine (CAS 2573217-06-6)
- 2-amino-3,1,4$l^{5}-[1,2$l^{5},4]thiadiazolo[2,3-a][1$l^{5}]pyridin-4-ylium chloride (CAS 36273-97-9)
- Ethyl 4-(2-((2,4-difluorophenyl)amino)-2-oxoethyl)piperazine-1-carboxylate (CAS 794556-68-6)
- Tert-butyl 7-bromo-6-nitro-3,4-dihydroisoquinoline-2(1H)-carboxylate (CAS 186390-63-6)
- 2-Amino-1-(4-hydroxyphenyl)ethan-1-one (CAS 77369-38-1)
- Insulin Degludec impurity 4 (CAS CATO-C4X-21574)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com