Mometasone Furoate EP Impurity G CAS 105102-22-5
| CAS No. | 105102-22-5 |
| Molecular Formula | C22H28Cl2O4 |
| Molecular Weight | 427.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Based on its molecular formula C22H28Cl2O4, Mometasone Furoate EP Impurity G contains a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 427.36 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
As a process- or degradation-related impurity, Mometasone Furoate EP Impurity G (CAS 105102-22-5, C22H28Cl2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
As a certified reference material (CRM), Mometasone Furoate EP Impurity G meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H28Cl2O4 |
| Molecular Weight | 427.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | >95% |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 1987 |
| Halogen Content | Cl-containing |
Related Mometasone Standards
- Mometasone Impurity 28 (CAS CATO-C4X-170428)
- Mometasone Impurity 50 (CAS 23776-75-2)
- Mometasone Furoate EP Impurity K (CAS 4647-20-5)
- Mometasone Furoate Impurity 25 (CAS CATO-C4X-170425)
- Mometasone Impurity 47 (CAS 223776-47-4)
- Mometasone Furoate EP Impurity O (CAS 24916-91-4)
- Mometasone Impurity 33 (CAS CATO-C4X-170433)
- Mometasone EP Impurity M (CAS 57780-86-6)
Recommended Standards
- 2-((4-Oxo-3,4-dihydroquinazolin-2-yl)thio)-N-(3-(1,1,2,2-tetrafluoroethoxy)phenyl)acetamide (CAS 1020252-65-6)
- Beclometasone Impurity 33 (CAS CATO-C4X-147433)
- 3-((((9h-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(trifluoromethyl)benzoic acid (CAS 1341486-14-3)
- Meclorisone (CAS 4732-48-3)
- Terbutaline Impurity 31 HBr (CAS 2459974-80-0)
- Valsartan Impurity 119 (CAS CATO-C4X-1057119)
- Clonazepam Impurity 3 (CAS 180854-85-7)
- 5-Cyclopropoxy-N4-methylpyridine-3,4-dicarboxamide (CAS 1243347-78-5)
- 951884-53-0 3,5-Dichloro-3',5'-dimethyl-4'-methoxybenzophenone MFCD09801556 (CAS 951884-53-0)
- 3-amino-5-(aminomethyl)benzonitrile (CAS 1369924-42-4)
- (p-Iodo-Phe7)-ACTH (4-10) (CAS 159600-82-5)
- (S)-1-Tetralol (CAS 53732-47-1)
- (S)-2-amino-3-(1-(tert-butoxycarbonyl)-1H-pyrazol-4-yl)propanoic acid (CAS 2387567-02-2)
- RGD-targeted Proapoptotic Peptide trifluoroacetate salt (CAS 2243207-09-0)
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