Mometasone Impurity 28 CAS CATO-C4X-170428
| CAS No. | CATO-C4X-170428 |
| Molecular Formula | C22H28Cl2O4 |
| Molecular Weight | 427.36 g/mol |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 427.36 g/mol gives Mometasone Impurity 28 distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
Mometasone Impurity 28 (CAS CATO-C4X-170428) is a certified pharmaceutical impurity reference standard with the molecular formula C22H28Cl2O4 and a molecular weight of 427.36 g/mol.
Owing to a flavonoid core, a hydroxyl group, an ether linkage, chlorine substitution, Mometasone Impurity 28 is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 427.36 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard supports related-substances testing and method development in line with ICH Q3A/Q3B guidance on impurity control, and is suitable for system suitability testing and forced-degradation studies.
CATO manufactures Mometasone Impurity 28 under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C22H28Cl2O4 |
| Molecular Weight | 427.36 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Halogen Content | Cl-containing |
Related Mometasone Standards
- Mometasone Furoate EP Impurity G (CAS 105102-22-5)
- Mometasone Impurity 50 (CAS 23776-75-2)
- Mometasone Furoate EP Impurity K (CAS 4647-20-5)
- Mometasone Furoate Impurity 25 (CAS CATO-C4X-170425)
- Mometasone Impurity 47 (CAS 223776-47-4)
- Mometasone Furoate EP Impurity O (CAS 24916-91-4)
- Mometasone Impurity 33 (CAS CATO-C4X-170433)
- Mometasone EP Impurity M (CAS 57780-86-6)
Recommended Standards
- Beclometasone Impurity 33 (CAS CATO-C4X-147433)
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Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com